ReviewAging and disease2025
Effective Therapeutic Strategies to Prevent Frailty and Falls in Community-Dwelling Older Adults.
Review in Aging and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- [Geriatric medicine shapes the Future : Recommendations for modern Geriatric Medicine that places older people and their needs at the centre].Zeitschrift fur Gerontologie und Geriatrie · 2026Review
- Development and Temporal Validation of Machine Learning Models for Hyponatremia Risk in Community-Dwelling Older Adults: A Nationwide Claims-Based Study.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty and the consequent risk of falls represent significant challenges for community-dwelling older adults, often leading to severe injuries, functional decline, and loss of independence. Falls typically result from multiple interacting risk factors, many of which are modifiable through targeted interventions. This mini-review focuses on evidence from randomized controlled trials evaluating effective therapeutic strategies to prevent frailty and falls. Comprehensive assessment and management of modifiable risk factors have been shown to significantly reduce fall incidence. Key interventions include community-based and home-based exercise programs emphasizing balance and strength training. Additionally, the treatment of osteoporosis is crucial to reducing the risk of fall-related fractures. Other modifiable risk factors, such as orthostatic hypotension, polypharmacy, environmental hazards, osteoporosis, malnutrition, and cognitive impairment, require targeted assessment and intervention. Despite these advances, further research is needed to optimize multifactorial interventions and tailor strategies to individual risk profiles. Innovative research directions now span from micro to macro levels, incorporating insights from animal models to human studies, aiming to unravel underlying mechanisms and develop personalized therapeutic strategies. This review discusses emerging evidence and new interdisciplinary research avenues that offer hope for mitigating frailty and preventing falls in community-dwelling older adults.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.