Evidence map›Paper›PMID 40542138›Full record

ArticleSurgical endoscopy2025

Modified low-cost EndoVac is safe and efficacious for treatment of postoperative leaks even at low pressures.

Sridhar Sundaram, Rahul Puri, Devyani Niyogi, Virendra Tiwari, Akhil Mahajan, Aditya Kale, Shaesta Mehta, Sabita Jiwnani, Prachi Patil

Abstract read
In one paragraph

Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Indigenous endoscopic vacuum-assisted closure therapy for esophageal leaks: A novel technique.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sridhar Sundaram *Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Homi Bhabha National Institute, Dr. E Borges Road, Parel, Mumbai, 400012, India. drsridharsundaram@gmail.com.ORCID http://orcid.org/0000-0002-2946-8534
Rahul Puri *Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Homi Bhabha National Institute, Dr. E Borges Road, Parel, Mumbai, 400012, India.
Devyani NiyogiDepartment of Surgical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Virendra TiwariDepartment of Surgical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Akhil MahajanDepartment of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Homi Bhabha National Institute, Dr. E Borges Road, Parel, Mumbai, 400012, India.
Aditya KaleDepartment of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Homi Bhabha National Institute, Dr. E Borges Road, Parel, Mumbai, 400012, India.
Shaesta MehtaDepartment of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Homi Bhabha National Institute, Dr. E Borges Road, Parel, Mumbai, 400012, India.
Sabita JiwnaniDepartment of Surgical Oncology, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.
Prachi PatilDepartment of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Homi Bhabha National Institute, Dr. E Borges Road, Parel, Mumbai, 400012, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative gastrointestinal leaks are often treated using Endoscopic Vacuum therapy (EndoVac). We aim to study the role of modified low-cost EndoVac (mEndoVac) for treatment of postoperative leaks when used at low pressure for upper GI and standard pressure for lower GI leaks.

methodsRetrospective review of prospectively maintained endoscopy database from January 2022 till March 2024 was done for patients who underwent treatment for upper and lower GI leaks using mEndoVac. All upper GI leaks were treated with low pressure (25-30 mmHg-modulated using Sinapi™) while lower GI leaks were treated with standard high pressure (125-150 mmHg). The primary outcome was clinical success (resolution of leak cavity).

resultsEighteen patients underwent mEndoVac for anastomotic leaks (14 post-esophagectomy leaks, 4 rectal leaks). mEndoVac therapy was started at median 6 days after detection of leak. Intracavitatory mEndoVac placement was done in all patients. Median of 3.5 sessions (2-7) were done. Clinical success was achieved in 88.8% cases (16/18). Mortality at 6 months was seen in 3 cases (16.6%). Complications were seen in 5 (27.7%) patients (all mild).

conclusionsmEndoVac is safe and effective even at lower pressure for upper GI leaks and at standard pressure for lower GI leaks.

Indexed as

Anastomotic LeakNegative-Pressure Wound TherapyAdultAgedAged, 80 and overEsophagectomyFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeComplicationsEndoscopic vacuum therapyLeaks

Identifiers

PMID40542138
PMCPMC12287198

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.