Evidence map›Paper›PMID 40543044›Full record

GuidelineUnited European gastroenterology journal2025

Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility.

Amir Mari, Francesco Calabrese, Andrea Pasta, Greta Lorenzon, Bas Weusten, Jutta Keller, Pierfrancesco Visaggi, Sabine Roman, Elisa Marabotto, Ram Dickman and 36 more

Erratum issuedAbstract readPractice Guideline
In one paragraph

Guideline in United European gastroenterology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Observational
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

46 authors.

Amir MariGastroenterology Unit, Nazareth EMMS Hospital, Nazareth, Israel.
Francesco CalabreseGastroenterology Unit, Department of Internal Medicine, University of Genoa, Genoa, Italy.ORCID 0009-0008-4706-1499
Andrea PastaGastroenterology Unit, Department of Internal Medicine, University of Genoa, Genoa, Italy.ORCID 0000-0003-1791-4506
Greta LorenzonDepartment of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
Bas WeustenDepartment of Gastroenterology, St Antonius Hospital, Nieuwegein, the Netherlands.
Jutta KellerIsraelitic Hospital Hamburg, Academic Hospital University of Hamburg, Hamburg, Germany.
Pierfrancesco VisaggiGastroenterology Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.ORCID 0000-0002-6985-5301
Sabine RomanDigestive Physiology, Hospices Civils de Lyon, Hopital E Herriot, Lyon I University, LabTAU INSERM, Lyon, France.
Elisa MarabottoGastroenterology Unit, Department of Internal Medicine, University of Genoa, Genoa, Italy.
Ram DickmanDivision of Gastroenterology, Rabin Medical Center, Beilinson Hospital, Tel-Aviv, Israel.ORCID 0000-0002-6477-2849
Jordi SerraDigestive System Research Unit, University Hospital Vall d'Hebron, Barcelona, Spain.ORCID 0000-0003-2120-6270
Nicola De BortoliGastroenterology Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Paola IovinoGastroenterology Unit, Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana University of Salerno, Salerno, Italy.ORCID 0000-0002-9568-0680
Daniel PohlDepartment of Gastroenterology, University Hospital Zurich, Zurich, Switzerland.
Dan DumitrascuIuliu Hatieganu University of Medicine and Pharmacy, Cluj County Clinical Emergency Hospotal, Cluj-Napoca, Romania.
Mentore RibolsiUnit of Gastroenterology and Digestive Endoscopy, Campus Bio Medico University, Rome, Italy.
Claudia BarberDigestive System Research Unit, University Hospital Vall d'Hebron, Barcelona, Spain.
Serhat BorDivision of Gastroenterology & Ege Reflux Team, School of Medicine, Ege University, Izmir, Turkey.
Mark FoxDigestive Function: Basel, Laboratory and Clinic for Motility Disorders and Functional Digestive Diseases, Centre for Integrative Gastroenterology, Arlesheim, Switzerland.ORCID 0000-0003-4394-5584
Rami SweissGI Physiology Unit, University College London Hospital, London, UK.
Vicente Lorenzo-ZunigaLa Fe University and Polytechnic Hospital/IISLaFe, Valencia, Spain.
Filiz AkyuzDepartment of Gastroenterology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
Matteo GhisaDepartment of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
Altay CelebiDepartment of Gastroenterology, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.
Fahmi ShibliInstitute of Gastroenterology and Hepatology, Emek Medical Center, Afula, Israel.
Rainer DziewasDepartment of Neurology and Neurorehabilitation, Klinikum Osnabrück - Academic Teaching Hospital of the University of Münster, Osnabrück, Germany.
Ismail Hakkı KalkanDepartment of Gastroenterology, Türkiye Yüksek Ihtisas Training and Research Hospital, Ankara, Turkey.
Jan TackTranslational Research Center for Gastrointestinal Disorders, University of Leuven, Leuven, Belgium.
Pere ClavéGastrointestinal Physiology Lab, Hospital de Mataró, Consorci Sanitari del Maresme, Mataró, Spain.
Silvia CarrionGastrointestinal Physiology Lab, Hospital de Mataró, Consorci Sanitari del Maresme, Mataró, Spain.
Ivy ChengAcademic Unit of Human Communication, Learning and Development, Faculty of Education, University of Hong Kong, Hong Kong, Hong Kong.
Noemi TomsenGastrointestinal Physiology Lab, Hospital de Mataró, Consorci Sanitari del Maresme, Mataró, Spain.
Omar OrtegaGastrointestinal Physiology Lab, Hospital de Mataró, Consorci Sanitari del Maresme, Mataró, Spain.
Sergio Marin RubioGastrointestinal Physiology Lab, Hospital de Mataró, Consorci Sanitari del Maresme, Mataró, Spain.
Nicole PizzorniDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, Milan, Italy.
Emilia MichouDepartment of Speech Language Therapy, School of Health Rehabilitation Sciences, University of Patras, Patras, Greece.
Julie ReganDepartment of Clinical Speech & Language Studies, Trinity College Dublin, Dublin, Ireland.
Shaheen HamdyDivision of Diabetes, Endocrinology and Gastroenterology, GI Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Nathalie RommelDepartment of Neurosciences, ExpORL, Deglutology, University of Leuven, Leuven, Belgium.
Martina ScharitzerDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Olle EkbergDepartment of Translational Medicine/Radiology, Lund University, Malmö, Sweden.
Antonio SchindlerDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, Milan, Italy.
Renee SpeyerSchool of Health Sciences, College of Medicine, Nursing & Health Sciences, University of Galway, Galway, Ireland.ORCID 0000-0003-2828-8897
Anna GillmanDepartment of Clinical Speech & Language Studies, Trinity College Dublin, Dublin, Ireland.
Frank ZerbibDepartment of Gastroenterology, CHU de Bordeaux, Centre Médico-Chirurgical Magellan, Hôpital Haut-Lévêque, INSERM CIC 1401, Université de Bordeaux, Bordeaux, France.ORCID 0000-0002-6802-2121
Edoardo V SavarinoDepartment of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.

Funding

United European Gastroenterology
6 · The paper itself

Abstract

Dysphagia is a prevalent symptom of the upper gastrointestinal tract causing health related consequences, impacting quality of life and is associated with global economic burden. Swallowing difficulties are classified into oropharyngeal dysphagia (OD) and esophageal dysphagia. Despite its clinical importance, dysphagia is associated with several uncertainties regarding its optimal diagnostic work-up and management, particularly, considering the progress with diagnostic modalities and technologies. A Delphi consensus was performed with experts from various disciplines who conducted a literature summary and voting process on 41 statements. Quality of evidence was evaluated using the grading of recommendations, assessment, development, and evaluation criteria. Consensus was reached for all the statements. The panel agreed with the definition and prevalence of esophageal and OD types. The role of endoscopy, high-resolution manometry, EndoFLIP, barium swallow and other imaging tests in evaluating esophageal dysphagia has reached overall strong agreement. Videofluoroscopic swallow study, alongside fiber-endoscopic evaluation of swallowing, as the methods of choice for the instrumental assessment of oropharyngeal dysfunction is a strong recommendation. Regarding treatment, a weak recommendation was achieved for the use of PPIs, calcium-channel blockers, nitrates, phosphodiesterase type 5 inhibitors, antidepressants or peppermint oil for the treatment of hypercontractile esophagus. A strong recommendation exists for endoscopic and surgical treatment of achalasia, while a weak recommendation is provided for other esophageal motility disorders. Regarding OD, a weak recommendation was achieved for swallow therapy, to improve swallowing mechanics, reduce symptoms, and enhance quality of life. Swallow therapy could be more effective when using validated assessment tools, consistent treatment parameters, and considering long-term follow-up. A multinational group of European experts summarized the current state of consensus on the definition, diagnosis, and management of dysphagia.

Indexed as

Deglutition DisordersGastroenterologyConsensusDeglutitionDelphi TechniqueEuropeHumansManometryQuality of LifeSocieties, Medicalbarium swallowDelphi consensusdiagnosisdysphagiaesophageal motility disordershigh resolution manometry (HRM)managementoropharyngeal dysphagiaworkup

Identifiers

PMID40543044
PMCPMC12269739

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.