Trial reportBMC oral health2025
A novel fully guided technique for botulinum toxin injection in lateral pterygoid muscle using muscle segmentation for TMJ disc displacement with reduction: a randomized controlled trial.
Trial report in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06633445 (Evaluation of 3D Guided Botulinum Toxin Type A Injection in Lateral Pterygoid Muscle for Management of Patients With Anterior Disc Displacement With Reduction), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of 3D Guided Botulinum Toxin Type A Injection in Lateral Pterygoid Muscle for Management of Patients With Anterior Disc Displacement With Reduction ( a Randomized Controlled Clinical Trial )
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effectiveness of fully guided botulinum toxin (BTX) injection in lateral pterygoid muscle (LPM) using muscle segmentation technique and compare it with electromyography (EMG) for management of symptomatic disc displacement with reduction (DDWR). MATERIALS AND
methodsThis prospective randomized controlled trial (RCT) included 20 patients suffering from DDWR. Patients were randomly allocated to two groups receiving BTX injection in LPM using fully guided technique of muscle segmentation for LPM in group I (study) while using EMG in group II (control). Evaluation was done for disc position after 3 months and for maximum interincisal opening (MIO), temporomandibular joint (TMJ) and LPM tenderness, and clicking after 1,3 and 6 months.
resultsMaximum interincisal opening showed reduction at 1-month follow-up, followed by significant improvement in both groups. Significant disappearance of clicking, reduction in LPM and TMJ tenderness and disc position reduction were detected in both groups. However, the difference between both groups was not statistically significant except in LPM tenderness, there was a statistically significant difference in favor of group I at 3-and 6- month follow-up.
conclusionThe findings suggest that the fully guided technique using muscle segmentation is a viable, cost-effective and reproducible alternative to EMG for BTX injection in LPM. CLINICAL RELEVANCE: The fully guided technique by muscle segmentation in LPM is as effective as EMG, providing 3D virtual augmented environment of the muscle with its surrounding skeletal and dental structures.
trial registrationThis prospective RCT has been retrospectively registered at Clinical Trials.gov with identification number: NCT06633445, 2024-10-01.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.