ArticleAmerican journal of surgery2025
The association of race and ethnicity with risk-reducing mastectomies in patients with non-BRCA mutations.
Article in American journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Impact of Ethnicity on the Uptake of Risk Reducing Mastectomy in Unaffected BRCA1/2 and PALB2 Carriers in Canada.Annals of surgical oncology · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
introductionWe compared rates of risk reducing mastectomies (RRM) in patients with breast cancer (BC)-related pathogenic variants.
methodsFemale patients ages ≥18 with a BC-related pathogenic variant, without a concurrent or prior BC diagnosis, were identified from a single academic center's database. Patients were stratified by BRCA mutations, high penetrance mutations (HPM), and moderate penetrance mutations (MPM). Race and ethnicity were classified as non-Hispanic White (NHW), non-Hispanic Black (NHB), non-Hispanic other (NHO), and Hispanic.
resultsOur study included 528 patients, which included 79.2 % (n = 418) NHW, 7.0 % (n = 37) NHB, 3.6 % (n = 19) NHO, and 3.4 % (n = 18) Hispanic patients. Overall, 16.5 % of patients underwent RRM: 18.4 % of NHW, 10.8 % of NHB, 5.6 % of Hispanic (p = 0.45). For NHB and Hispanic patients, no individuals with HPMs (NHB 0/6, Hispanic 0/5) or MPMs (NHB 0/11, Hispanic 0/4) underwent RRM.
conclusionsOur findings suggest that race and ethnicity may be associated with the decision to undergo RRM.
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