ArticleBMJ open diabetes research & care2025
Fasting plasma glucose outperformed 1-hour plasma glucose in predicting diabetes incidence in individuals with family history of young-onset type 2 diabetes.
Article in BMJ open diabetes research & care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionFamily history (FmH) of young-onset type 2 diabetes (YOD) and 1-hour plasma glucose (PG) during the 75-g oral glucose tolerance test predicts incident diabetes, although their interactions remain unknown. RESEARCH DESIGN AND
methodsIn a workforce cohort established in 1998-2003, we ascertained their glycemic status in 2012-2014. We examined the interaction between FmH-YOD and 1-hour PG in predicting diabetes and used receiver operating characteristics (ROC) analysis to compare the performance of 1-hour PG in participants with or without FmH-YOD.
resultsAmong 583 participants (median age (IQR)=41 (36-47) years, 43.7% men, body mass index=23.3 (21.2-26) kg/m
conclusionsFPG outperformed 1-hour PG in predicting incident diabetes in people with FmH-YOD, calling for precise classification and preventive strategies.
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