ArticleWorld journal of gastrointestinal oncology2025
Prognostic value of preoperative fibrinogen, neutrophil-to-lymphocyte ratio, serum alpha-fetoprotein, and prealbumin for patients with primary liver cancer undergoing transarterial chemoembolization.
Article in World journal of gastrointestinal oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Correction to "Prognostic value of preoperative fibrinogen, neutrophil-to-lymphocyte ratio, serum alpha-fetoprotein, and prealbumin for patients with primary liver cancer undergoing transarterial chemoembolization".World journal of gastrointestinal oncology · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary liver cancer, predominantly hepatocellular carcinoma (HCC), is a major cause of cancer-related mortality. Transarterial chemoembolization (TACE) is a key palliative option for unresectable HCC. However, prognostic outcomes after TACE vary significantly. This study evaluated the prognostic value of the fibrinogen and neutrophil-to-lymphocyte ratio (F-NLR) score, serum alpha-fetoprotein (AFP), and prealbumin (PA) in patients undergoing TACE.
aimTo investigate the prognostic significance of F-NLR score, AFP, and PA in patients undergoing TACE.
methodsVariables such as F-NLR score, AFP, PA, and other clinical indicators were assessed. Follow-ups determined prognosis as good or poor. Statistical assessments, including receiver operating characteristic analyses, were performed to evaluate the prognostic significance and develop an integrated predictive model.
resultsA retrospective analysis of 162 patients with primary liver cancer undergoing TACE was conducted. Low F-NLR scores and AFP levels and high PA were significantly associated with a good prognosis. The combined model, which integrated F-NLR, AFP, and PA, demonstrated a favorable prognostic predictive capability, with an area under the curve of 0.933.
conclusionPreoperative F-NLR, AFP, and PA are valuable prognostic predictors in patients with HCC undergoing TACE.
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