Evidence map›Paper›PMID 40547295›Full record

SynthesisFrontiers in bioengineering and biotechnology2025

Dynamic behavior of the nucleus pulposus within the intervertebral disc loading: a systematic review and meta-analysis exploring the concept of dynamic disc model.

Jean-Philippe Deneuville, Maxime Billot, Alexandra Cervantes, Sylvain Peterlongo, Martin Meyer, Mezika Kolder, Marie Escande, Mathilde Bourgeois, Adrien Pallot, Romain David and 7 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jean-Philippe DeneuvillePRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, Poitiers, France.
Maxime BillotPRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, Poitiers, France.
Alexandra CervantesAssociation Francophone McKenzie (AFMcK - McKenzie Francophonic Association), Paris, France.
Sylvain PeterlongoAssociation Francophone McKenzie (AFMcK - McKenzie Francophonic Association), Paris, France.
Martin MeyerAssociation Francophone McKenzie (AFMcK - McKenzie Francophonic Association), Paris, France.
Mezika KolderAssociation Francophone McKenzie (AFMcK - McKenzie Francophonic Association), Paris, France.
Marie EscandeCentre Européen d'Enseignement en Rééducation et Réadaptation Fonctionnelle (CEERRF - European Center for Education in Rehabilitation and Functional Rehabilitation), Saint Denis, France.
Mathilde BourgeoisCentre Européen d'Enseignement en Rééducation et Réadaptation Fonctionnelle (CEERRF - European Center for Education in Rehabilitation and Functional Rehabilitation), Saint Denis, France.
Adrien PallotCentre Européen d'Enseignement en Rééducation et Réadaptation Fonctionnelle (CEERRF - European Center for Education in Rehabilitation and Functional Rehabilitation), Saint Denis, France.
Romain DavidPRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, Poitiers, France.
Manuel RoulaudPRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, Poitiers, France.
Amine OunajimPRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, Poitiers, France.
Mark LaslettThe Sports Clinic, Christchurch, New Zealand.
Mathieu SarracanieCenter for Adaptable MRI Technology, Institute of Medical Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom.
Najat SalamehCenter for Adaptable MRI Technology, Institute of Medical Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom.
Arnaud GermaneauInstitut Pprime UPR 3346, CNRS - Université de Poitiers - ISAE-ENSMA, Poitiers, France.
Philippe RigoardPRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, Poitiers, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The dynamic disc model (DDM) is a theoretical framework in spine mechanics that theorizes the behavior of the Methods: We screened seven databases (CENTRAL, Embase, MEDLINE, CINAHL, ScienceDirect, Google Scholar, and HAL) up to July 2024, identifying studies through a PRISMA-guided approach that detailed the mechanical transformation (displacement and deformation) of the Results: From the 9,269 articles screened, 14 studies were included in the systematic review and meta-analysis. Magnetic Resonance Imaging (MRI) was employed in 92.8% of the studies, revealing four strategies for assessing Conclusion: Evidence for the dynamic disc model for intact discs is of low strength, whereas very limited evidence challenges the dynamic disc model for fissured discs. New multiparametric MRI studies may help guiding future clinical assessment protocols. Systematic Review Registration: CRD42022331774.

Indexed as

directional preferencedynamic disc modelintervertebral disc biomechanicslow back painsystematic review/meta-analysis

Identifiers

PMID40547295
PMCPMC12179537

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.