Evidence map›Paper›PMID 40547318›Full record

ArticleObesity science & practice2025

Impact of Obesity on Appetite-Related Behaviors and Biomarkers in Older Adults: A Cross-Sectional Study.

Sean J Iwamoto, Tanya M Halliday, Jason R Tregellas, Kristina T Legget, Allison K Hild, Marc-André Cornier

Abstract read
In one paragraph

Article in Obesity science & practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sean J IwamotoDivision of Endocrinology, Metabolism and Diabetes Department of Medicine University of Colorado School of Medicine Anschutz Medical Campus Aurora Colorado USA.ORCID https://orcid.org/0000-0002-7316-8256
Tanya M HallidayDepartment of Health and Kinesiology University of Utah Salt Lake City Utah USA.
Jason R TregellasResearch Service Rocky Mountain Regional Veterans Affairs Medical Center Aurora Colorado USA.
Kristina T LeggetResearch Service Rocky Mountain Regional Veterans Affairs Medical Center Aurora Colorado USA.
Allison K HildDepartment of Psychiatry University of Colorado School of Medicine Anschutz Medical Campus Aurora Colorado USA.
Marc-André CornierDivision of Endocrinology, Metabolism and Diabetes Department of Medicine University of Colorado School of Medicine Anschutz Medical Campus Aurora Colorado USA.

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS · 1995 to 2026
$32.6M
NIDDK National Research Service Award (NRSA) T32 Diversity Administrative SupplementT32DK007658 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Kristen Elizabeth Boyle, Ihuoma U Eneli · 1991 to 2026
$6.0M
Neuronal and behavioral effects of an implicit priming approach to improve eating behaviors in obesity: Diversity supplement.R01DK125417 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI TREGELLAS, JASON R · 2021 to 2025
$2.7M
Sex-based differences in the neuronal mechanisms of food intake behaviorR01DK119236 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI LEGGET, KRISTINA T · 2019 to 2023
$2.6M
CSRD VA I01 CX001414CSRD VA I01 CX001949CSRD VA IK6 CX002178NCATS NIH HHS UL1 TR002535NIDDK NIH HHS P30 DK048520NIDDK NIH HHS R01 DK119236NIDDK NIH HHS R01 DK125417NIDDK NIH HHS T32 DK007658
6 · The paper itself

Abstract

Objective: Although aging is associated with reduced hunger and energy intake (EI), obesity is increasing in older adults. This study aimed to identify appetite regulation differences between older adults with obesity and older adults with normal weight (NW). Methods: This cross-sectional study recruited older adults with obesity (BMI 30-40 kg/m Results: 13 older adults with obesity (aged 70.8 ± 4.0 years, 54% female, BMI 33.1 ± 3.6 kg/m Conclusion: Despite similar meal-related appetite and EI, older adults with obesity had higher fasting disinhibition, perceived hunger, GLP-1 and insulin, higher PYY and insulin iAUCs, and lower confidence in preventing overeating than those with NW. These differences between older adults with obesity and NW have implications for tailored obesity treatments in older adults.

Indexed as

agingappetiteenergy intakeobesityolder adults

Identifiers

PMID40547318
PMCPMC12180562

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.