Evidence map›Paper›PMID 40547469›Full record

ArticleFrontiers in public health2025

Investigation of human infection with H5N6 avian influenza cases in Sichuan Province from 2014 to 2024: a retrospective study.

Lijun Zhou, Zhirui Li, Xingyu Zhou, Lin Zhao, Huanwen Peng, Xunbo Du, Jianping Yang, Fengmiao Hu, Shuang Dong, Baisong Li and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Lijun Zhou *Department of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, China.
Zhirui Li *Department of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, China.
Xingyu ZhouDepartment of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, China.
Lin ZhaoNanchong Center for Disease Control and Prevention, Nanchong, China.
Huanwen PengDazhou Center for Disease Control and Prevention, Nanchong, China.
Xunbo DuChengdu Center for Disease Control and Prevention, Chengdu, China.
Jianping YangBazhong Center for Disease Control and Prevention, Bazhong, China.
Fengmiao HuDepartment of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, China.
Shuang DongDepartment of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, China.
Baisong LiChongqing Center for Disease Control and Prevention, Chongqing, China.
Guidan LiuZigong Center for Disease Control and Prevention, Zigong, China.
Hongyu TangDeyang Center for Disease Control and Prevention, Deyang, China.
Xiao LeiLeshan Municipal Center for Disease Control and Prevention, Leshan, China.
Xiaojuan WangLuzhou Center for Disease Control and Prevention, Luzhou, China.
Shunning ZhaoZiyang Center for Disease Control and Prevention, Ziyang, China.
Ping ZhouYibin Center for Disease Control and Prevention, Yibin, China.
Heng YuanDepartment of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, China.
Chongkun XiaoDepartment of Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective is to examine the epidemiology and clinical features of human cases infected with H5N6 avian influenza in Sichuan Province from 2014 to 2024, and to offer guidance for the prevention and management of human infections with H5N6 avian influenza. Methods: Epidemiological survey reports of H5N6 avian influenza cases in Sichuan Province from 2014 to 2024 were compiled, and the epidemiological context and characteristics of 16 human cases infected with H5N6 avian influenza in the province were summarized and analyzed using descriptive epidemiological methods. Results: From 2014, when the initial human case ofH5N6 infection was documented in Sichuan Province, to 2024, there have been 16 human cases of H5N6 avian influenza in the region, resulting in 12 fatalities and a case fatality rate of 75%. The instances were predominantly located in the Chengdu Plain, eastern Sichuan, and southern Sichuan. Conclusion: Human instances of H5N6 avian influenza in Sichuan Province exhibit no discernible periodicity, and entail significant fatality rates. It is essential to enhance the early diagnosis and treatment of avian influenza cases in medical facilities, prioritize farmers with preexisting conditions who have been in contact with deceased poultry, conduct influenza virus testing promptly, and administer antiviral medications at the earliest opportunity. Simultaneously, we must effectively engage in public awareness and education for the populace, manage poultry scientifically, and prevent direct contact with deceased poultries.

Indexed as

Influenza, HumanInfluenza in BirdsAdolescentAdultAgedAnimalsChinaFemaleHumansMaleMiddle AgedPoultryRetrospective StudiesYoung AdultavianepidemiologyH5N6influenzapoultry diseases

Identifiers

PMID40547469
PMCPMC12179061

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.