Evidence map›Paper›PMID 40547764›Full record

ArticleJournal of family medicine and primary care2025

The impact of overweight-obesity on heart rate variability among Indian adults - A cross-sectional study.

Shobitha Muthukrishnan, Shilpi Vashishta, Shilpi Bhat

Abstract read
In one paragraph

Article in Journal of family medicine and primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shobitha MuthukrishnanProfessor and Head, Department of Physiology, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India.
Shilpi VashishtaAssistant Professor, Department of Physiology, Government Medical College, Satna, Madhya Pradesh, India.
Shilpi BhatSenior Tutor, Department of Physiology, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Overweight-obesity is one of the leading disorders that elevate all-cause mortality in patients with an increased body mass index (BMI), contributing to deaths from cardiovascular disease (CVD). One plausible explanation for the higher CVD in obese individuals is cardiac autonomic dysfunction. Previous studies done on overweight-obesity are majorly based on internationally accepted diagnostic cutoffs for BMI and waist circumference. Assessments in overweight and obese young Indian Adults as per the standards published in the Indian ministry's Consensus Guidelines for the Prevention and Management of Obesity and Metabolic Syndrome are very limited. Objective: To assess and classify the BMI of Indian subjects according to the Asian standard of BMI classification as normal weight, overweight, or obese and to compare heart rate variability (HRV) between overweight, obese, and normal weight healthy adults. Methods: The research involved a total of 157 participants aged 18 to 40 years. According to the Asian standard of BMI classification, 50 subjects with BMI > 25 kg/m² were classified as obese and 53 subjects with BMI between 23 and 25 kg/m² were categorized as overweight. Fifty-four subjects with BMI in the range of 18-22.9 kg/m² were healthy adult controls. Standard procedures were employed to assess short-term HRV characteristics. The ANOVA test was used to compare data across the groups. Results: The results reflect that time domain measures like SDNN, RMSSD, and pNN50% and frequency domain measures like HF (msec Conclusion: The study found that both overweight and obese young individuals exhibited altered characteristics of the autonomic nervous system, resulting in reduced parasympathetic activity and diminished heart rate variability. Increasing BMI was strongly associated with reduced cardiac parasympathetic and increased sympathetic activity in both overweight and obese individuals. Therefore, timely identification and early intervention in the initial overweight stage through weight loss is a dire necessity to prevent the progression to obesity and its cardiovascular complications.

Indexed as

Body mass index (BMI)cardiac autonomic regulationheart rate variability (HRV)obesityoverweight

Identifiers

PMID40547764
PMCPMC12178469

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.