Evidence map›Paper›PMID 40547947›Full record

ArticleClinical & translational immunology2025

Functional characterisation of CD8

Anna Strömberg, Mirko Mandić, Brennan J Wadsworth, Sebastian Proschinger, Seher Alam, Lisa Mj Eriksson, Laura Barbieri, Eric Rullman, Helene Rundqvist

Abstract read
In one paragraph

Article in Clinical & translational immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Exercise and CD8Journal of molecular medicine (Berlin, Germany) · 2026
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna StrömbergDivision of Clinical Physiology, Department of Laboratory Medicine Karolinska Institute Stockholm Sweden.ORCID https://orcid.org/0009-0002-6719-4535
Mirko MandićDivision of Clinical Physiology, Department of Laboratory Medicine Karolinska Institute Stockholm Sweden.
Brennan J WadsworthDepartment of Cell and Molecular Biology Karolinska Institute Stockholm Sweden.
Sebastian ProschingerDivision of Performance and Health (Sports Medicine), Institute for Sport and Sport Science TU Dortmund University Dortmund Germany.
Seher AlamDivision of Clinical Physiology, Department of Laboratory Medicine Karolinska Institute Stockholm Sweden.
Lisa Mj ErikssonDivision of Clinical Physiology, Department of Laboratory Medicine Karolinska Institute Stockholm Sweden.
Laura BarbieriGraduate School of Medicine/Osaka International Research Center for Infectious Diseases Osaka Metropolitan University Osaka Japan.
Eric RullmanDivision of Clinical Physiology, Department of Laboratory Medicine Karolinska Institute Stockholm Sweden.
Helene RundqvistDivision of Clinical Physiology, Department of Laboratory Medicine Karolinska Institute Stockholm Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The beneficial influence of exercise on outcomes such as infection control and cancer prevention has been attributed partly to the immune system response during physical exertion. CD8 Methods: CD8 Results: Exercise led to a threefold increase in CD8 Conclusion: The pronounced increase in the total number of circulating CD8

Indexed as

CD8+ T cellscytotoxicityexerciseflow cytometryimmune surveillancemetabolism

Identifiers

PMID40547947
PMCPMC12179809

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.