Evidence map›Paper›PMID 40548320›Full record

ArticlePsychiatric research and clinical practice2025

Psychotropic Drugs for Older Adults With Psychiatric Disorders Presenting to the Emergency Department: Prescription Patterns and Treatment Outcomes.

Marianna Mazza, Marcello Covino, Francesco Maria Lisci, Caterina Brisi, Georgios D Kotzalidis, Giuseppe Marano, Francesca Abate, Maria Benedetta Anesini, Gianluca Boggio, Michele Ciliberto and 9 more

Abstract read
In one paragraph

Article in Psychiatric research and clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Marianna MazzaUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Marcello CovinoEmergency Medicine Department Fondazione Policlinico Universitario Agostino Gemelli IRCCS Università Cattolica del Sacro Cuore Rome Italy.
Francesco Maria LisciUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Caterina BrisiUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Georgios D KotzalidisUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Giuseppe MaranoUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.ORCID https://orcid.org/0000-0001-7058-4927
Francesca AbateUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Maria Benedetta AnesiniUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Gianluca BoggioUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Michele CilibertoUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Valeria De MasiUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Cecilia FalsiniUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Ester Maria MarzoUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Sara RossiUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Maria Chiara SperaUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Alberto TorresiUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.
Benedetta SimeoniEmergency Medicine Department Fondazione Policlinico Universitario Agostino Gemelli IRCCS Università Cattolica del Sacro Cuore Rome Italy.
Francesco FranceschiEmergency Medicine Department Fondazione Policlinico Universitario Agostino Gemelli IRCCS Università Cattolica del Sacro Cuore Rome Italy.
Gabriele SaniUnit of Psychiatry Fondazione Policlinico Universitario Agostino Gemelli IRCCS Rome Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: A high proportion of patients presenting to Emergency Departments (EDs) consists of vulnerable elderly people. Mental illnesses are frequently related to advancing age, with difficult to detect symptoms. The aim of this study was to investigate psychiatric drug use by geriatric patients in an ED for whom a psychiatric consultation was needed, according to their psychopathology and severity of outcome. Methods: During 2014 to 2023, 342 aged patients (35.96% men and 64.04% women; median age = 73 years, range 68-79 years) sought help at the ED of our hospital and required psychiatric consultation. Results: Male sex, nonsuicidal self-harm, and access through emergency medical services were predictors of >48-h ED stay/hospital admission (the main severity outcome). Patients with bipolar disorder (BD) and psychotic disorders were more socially disadvantaged and with significantly longer length of stay at the ED than the other groups. Additionally, BD patients had more psychiatric drug prescriptions at discharge than patients in the other diagnostic groups. Current nonsuicidal self-harm emerged as a predictor of >48-h ED stay/hospital admission. Conclusions: Future studies should focus on investigating suicide risk in ED contexts, on correct diagnosing and on prescription appropriateness of medications in older adults with psychiatric disorders referring to the ED so to tailor-cut treatment on individual patients' needs. Relevant to Clinical Practice: This study highlights the significant impact of psychiatric conditions on healthcare utilization among elderly patients presenting to the ED. The findings emphasize the need for improved diagnosis and management of psychiatric disorders, medication optimization, and tailored treatment approaches.

Identifiers

PMID40548320
PMCPMC12178202

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.