SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Risk factors for chemotherapy-induced oral mucositis in cancer patients: a systematic review and meta-analysis.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Italian regional data and oropharyngeal adverse events to drugs and vaccines: insights from a 3-year spontaneous reporting (2022-2024).Pharmacological reports : PR · 2026Article
- A double layer oral film loaded with doxepin hydrochloride for the treatment of chemotherapy-induced oral mucositis.Frontiers in pharmacology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis systematic review aims to identify the factors influencing chemotherapy-induced oral mucositis in cancer patients.
methodsA comprehensive literature search was conducted across PubMed, Web of Science, Embase, The Cochrane Library, VIP, Wanfang, CNKI, CBM, and CINAHL from the establishment of the databases to August 2024. Meta-analysis was performed using RevMan5.4 software, with odds ratios (OR) and 95% confidence intervals (CI) used to assess the risk factors. Methodological quality was assessed using the Newcastle-Ottawa Scale (NOS) and the evaluation criteria recommended by the Agency for Healthcare Research and Quality (AHRQ). The quality of evidence was graded using the GRADEpro GDT.
resultsThe analysis included 10 studies with a total of 2365 patients. Six studies were of high quality, and four studies were of moderate quality. The results indicated that the following factors were associated with an increased risk of chemotherapy-induced oral mucositis (CIOM) in cancer patients: a history of oral disease, combination chemotherapy, smoking history, oral hygiene, and chemotherapy regimens containing 5-FU/methotrexate.
conclusionThis meta-analysis identified several potential independent risk factors for CIOM in cancer patients. Early screening and timely intervention for patients with these risk factors are crucial for reducing the likelihood of CIOM and improving overall prognosis.
Indexed as
Identifiers
40549169What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.