Evidence mapPaperPMID 40549260Full record

ArticleMagma (New York, N.Y.)2025

Comparison between fast-interrupted steady-state (FISS) and rapid water-excitation pulses for fat signal suppression in free-running whole-heart MRI at 1.5 T.

Yasaman Safarkhanlo, Jérôme Yerly, Mariana B L Falcão, Adèle L C Mackowiak, Davide Piccini, Matthias Stuber, Bernd Jung, Christoph Gräni, Jessica A M Bastiaansen

Abstract readComparative Study
In one paragraph

Article in Magma (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yasaman SafarkhanloDepartment of Cardiology, University Hospital Bern, Bern, Switzerland.
Jérôme YerlyDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV), University of Lausanne (UNIL), Lausanne, Switzerland.
Mariana B L FalcãoDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV), University of Lausanne (UNIL), Lausanne, Switzerland.
Adèle L C MackowiakTranslation Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland.
Davide PicciniDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV), University of Lausanne (UNIL), Lausanne, Switzerland.
Matthias StuberDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV), University of Lausanne (UNIL), Lausanne, Switzerland.
Bernd JungTranslation Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland.
Christoph GräniDepartment of Cardiology, University Hospital Bern, Bern, Switzerland.
Jessica A M BastiaansenTranslation Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland. jbastiaansen.mri@gmail.com.ORCID http://orcid.org/0000-0002-5485-1308

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung PCEFP2_194296
6 · The paper itself

Abstract

backgroundFree-running whole-heart MRI using balanced steady-state free precession (bSSFP) sequences offer high SNR and myocardial tissue contrast. However, an inadequate fat signal suppression may introduce artifacts and is particularly challenging with non-Cartesian readouts. The aim of this study was to evaluate different fat-signal suppression methods for whole-heart free-running MRI at 1.5 T using numerical simulations, phantom, and cardiac MRI experiments without the use of contrast agents.

methodsBinomial off-resonant rectangular (BORR), lipid insensitive binomial off-resonant RF excitation (LIBRE), and lipid insensitive binomial off-resonant (LIBOR) pulses were implemented within a 3D radial bSSFP sequence. Their pulse parameters were optimized for fat signal suppression at 1.5 T using simulations and phantom experiments. Optimized protocols, along with a free-running fast interrupted steady-state (FISS) and non-fat suppressed bSSFP sequence, were used to acquire phantom and cardiac data in five volunteers. SAR values were recorded. The SNR and CNR

resultsLIBOR had the highest CNR

conclusionThe tested sequences performed similarly in SNR and CNR but LIBOR offered the lowest SAR, making it a promising candidate for applications where RF energy deposition is a concern.

Indexed as

Adipose TissueHeartMagnetic Resonance ImagingAdultAlgorithmsArtifactsComputer SimulationContrast MediaFemaleHealthy VolunteersHumansImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedImaging, Three-DimensionalMaleMyocardiumContrast MediaWater1.5 T5D whole-heart free-running CMRbSSFPFat suppressionFISSLIBREOff-resonance

Identifiers

PMID40549260
PMCPMC12638339

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.