Evidence map›Paper›PMID 40550087›Full record

ReviewMedicine2025

Research on mammary gland hyperplasia compound patents' herbal combination rules based on complex system entropy clustering: A review.

Xujie Yang, Xiaohua Pei, Hong Zhang, Wanyue Zhang

Abstract readReview
In one paragraph

Review in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xujie YangDepartment of Medical History Literature, Hebei University of Chinese Medicine, Hebei, China.ORCID 0000-0001-8537-2644
Xiaohua PeiXiamen Hospital, Beijing University of Chinese Medicine, Traditional Chinese Medicine Surgery, Fujian, China.
Hong ZhangDepartment of Medical History Literature, Hebei University of Chinese Medicine, Hebei, China.
Wanyue ZhangDepartment of Medical History Literature, Hebei University of Chinese Medicine, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the combination rules of herbal compound patents for the treatment of mammary gland hyperplasia (MGH). Herbal compound patents (oral drugs) for the treatment of MGH from the past 31 years were collected, and a database was created. Complex system entropy clustering was used to analyze the prescription rule of herbal compound patents for the treatment of MGH. In total, 765 MGH herbal compound authorized patents, including 136 Chinese herbs, were identified. High-frequency herbs, herbal pairs, and core associations were obtained by complex system entropy clustering. MGH herbal compound patents are known to activate blood circulation, remove stasis, soothe the liver, regulate Qi, clear heat, detoxify, reduce lumps, soften hard mass, dissolve knots, eliminate phlegm, resolve stagnation, expel pus, tonify Qi and blood, nourish Yin-essence, and generate muscle. A combination of 2 or more effective herbs can achieve stronger therapeutic effects (such as activate blood circulation + activate Qi circulation, supplement blood + promote blood circulation, nourish blood + promote Qi circulation, soothe the liver + promote blood circulation, soothe the liver + promote Qi circulation, soothe the liver + soften lumps and dissipate nodules, reduce swelling/dissipate nodules + promote Qi circulation, promote Qi circulation + reduce swelling/discharge pus, promote Qi circulation + tonify spleen/promote water metabolism/clear damp, reduce swelling/disperse nodules/discharge pus + activate blood circulation, etc). The correlation of MGH with herbal compound patents can be effectively analyzed by complex system entropy clustering.

Indexed as

Drugs, Chinese HerbalMammary Glands, HumanPatents as TopicCluster AnalysisEntropyFemaleHumansHyperplasiaDrugs, Chinese Herbalcomplex systementropy clusterherbal compoundmammary gland hyperplasiaprescription rule

Identifiers

PMID40550087
PMCPMC12187359

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.