Evidence map›Paper›PMID 40550993›Full record

Trial reportEuropean geriatric medicine2025

Feasibility of a web video-based positive word stimulation program for older patients with cardiac disease and subthreshold depression admitted to an acute care ward: a pilot randomized controlled trial.

Masataka Sakimoto, Hiroyuki Uchida, Takumi Igusa, Takuya Kobayashi, Aya Fukazawa, Chihaya Machida, Hirokuni Fujii, Keisuke Sekine, Minori Kurosaki, Kenji Tsuchiya and 2 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in European geriatric medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Masataka SakimotoGraduate School of Health Sciences, Gunma University, Maebashi, Japan.
Hiroyuki UchidaGraduate School of Health Sciences, Gunma University, Maebashi, Japan.
Takumi IgusaGraduate School of Health Sciences, Gunma University, Maebashi, Japan.
Takuya KobayashiGraduate School of Health Sciences, Gunma University, Maebashi, Japan.
Aya FukazawaDepartment of Rehabilitation, Fujioka General Hospital, Fujioka, Japan.
Chihaya MachidaGraduate School of Health Sciences, Gunma University, Maebashi, Japan.
Hirokuni FujiiDepartment of Rehabilitation, Fujioka General Hospital, Fujioka, Japan.
Keisuke SekineDepartment of Rehabilitation, Fujioka General Hospital, Fujioka, Japan.
Minori KurosakiDepartment of Rehabilitation, Fujioka General Hospital, Fujioka, Japan.
Kenji TsuchiyaDepartment of Rehabilitation, Faculty of Health Sciences, Nagano University of Health Medicine, Nagano, Japan.
Senichiro KikuchiGraduate School of Health Sciences, Gunma University, Maebashi, Japan.
Kazuki HiraoDepartment of Occupational Therapy, School of Health Sciences, Faculty of Medicine, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan. kazuki.hirao@health.nop.kagoshima-u.ac.jp.ORCID http://orcid.org/0000-0002-2467-7564

Funding

Japan Society for the Promotion of Science 22K11111
6 · The paper itself

Abstract

purposeMajor depressive disorder can exacerbate morbidity and hasten mortality from cardiac disorders among geriatric patients, so mitigation of subthreshold depression (StD) may help improve long-term outcome. Subliminal priming with supraliminal reward stimulation (SPSRS), in which subjects view videos with embedded positive words, may be an effective intervention strategy for StD symptom reduction. The purpose of this pilot randomized controlled trial (RCT) was to evaluate the feasibility of an SPSRS intervention for older patients with cardiac disease and StD admitted to acute care wards.

methodsThirty older patients with cardiac disease and comorbid StD (79.2 ± 7.55 years, six female) were randomly assigned to the intervention (SPSRS) group (n = 15) or the control group (n = 15). The intervention group viewed 10-min videos containing positive word stimulation once per day for 5 consecutive days, while the control group viewed YouTube videos containing no positive word stimulation following the same protocol. The primary outcome was a change in score on the Japanese version of the Beck Depression Inventory-II (BDI-II).

resultsThere were no dropouts and no adverse events during the trial. Linear mixed models showed no significant improvement in BDI-II in the intervention group compared to the control group (P = 0.72).

conclusionsThis pilot RCT supports the feasibility of the SPSRS intervention for older patients with cardiac disease and StD. A full-scale RCT would require a larger sample size, modifications to the content for this patient group, increased frequency of daily interventions, and a more sensitive depression symptom assessment tool.

trial registrationThe University Hospital Medical Information Network (UMIN) Registered 8 September 2023 (UMIN000052155).

Indexed as

DepressionHeart DiseasesAgedAged, 80 and overFeasibility StudiesFemaleHumansInternetMalePilot ProjectsPsychiatric Status Rating ScalesTreatment OutcomeVideo RecordingCardiac diseaseMental healthOlder adultsSubthreshold depression

Identifiers

PMID40550993
PMCPMC12528300

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.