Evidence map›Paper›PMID 40551892›Full record

ArticleFrontiers in endocrinology2025

Correlation between serum 25-hydroxyvitamin D levels and peripheral neuropathy in type 2 diabetes mellitus.

Senzhen Chen, Jinfeng Chen, Shujing Zheng, Yiling Yan, Mengting Huang, Nuoqi Chen

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Senzhen ChenZhangzhou Affiliated Hospital of Fujian Medical University, The Second Department of Endocrinology and Metabolism, Zhangzhou, Fujian, China.
Jinfeng ChenZhangzhou Affiliated Hospital of Fujian Medical University, The Second Department of Endocrinology and Metabolism, Zhangzhou, Fujian, China.
Shujing ZhengZhangzhou Affiliated Hospital of Fujian Medical University, Department of Pathology, Zhangzhou, Fujian, China.
Yiling YanZhangzhou Affiliated Hospital of Fujian Medical University, Department of Clinical Nutrition, Zhangzhou, Fujian, China.
Mengting HuangFujian Medical University, Department of Clinical Medicine, Fuzhou, Fujian, China.
Nuoqi ChenZhangzhou Affiliated Hospital of Fujian Medical University, The Second Department of Endocrinology and Metabolism, Zhangzhou, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the correlation between serum 25-hydroxyvitamin D (25[OH]D) levels and diabetic peripheral neuropathy (DPN) in type 2 diabetes mellitus (T2DM) and to evaluate its predictive value for DPN. Methods: Participants were divided into three groups based on 25(OH)D levels: deficient, insufficient, and normal. The relationship between 25(OH)D and DPN, as well as the correlation of 25(OH)D and DPN with various indicators, was analyzed. Results: Compared to the non-DPN group (NDPN), the DPN group had significantly lower levels of 25(OH)D3 (22.10 ± 0.77 vs. 24.45 ± 0.66 ng/mL) and total 25(OH)D (23.12 ± 0.74 vs. 25.68 ± 0.67 ng/mL). In addition, significant differences were observed in body mass index (BMI), resting heart rate (RHR), triglyceride (TG), free triiodothyronine (FT3), and blood urea nitrogen (BUN) between the two groups ( Conclusion: Serum 25(OH)D levels can serve as a simple and effective screening tool to predict the occurrence of DPN in patients with T2DM.

Indexed as

Diabetes Mellitus, Type 2Diabetic NeuropathiesVitamin DVitamin D DeficiencyAdultAgedBiomarkersFemaleHumansMaleMiddle AgedROC Curve25-hydroxyvitamin DBiomarkersVitamin DDPNliquid chromatography-tandem mass spectrometry (LC-MS/MS)NDPNserum 25-hydroxyvitamin Dtype 2 diabetes mellitus

Identifiers

PMID40551892
PMCPMC12183018

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.