Evidence map›Paper›PMID 40552170›Full record

ReviewJournal of aging research2025

Evaluating the Effectiveness of Cognitive Interventions for Healthy and Mild Cognitive Impairment Adults: A Comprehensive Umbrella Meta-Analysis.

Giuseppe Forte, Francesca Favieri, Ilaria Corbo, Ilaria Chirico, Rabih Chattat, Anna Maria Della Vedova, Anna Pecchinenda, Maria Casagrande

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of aging research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giuseppe ForteDepartment of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0002-5223-041X
Francesca FavieriDepartment of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0002-6696-5855
Ilaria CorboDepartment of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0002-7070-3751
Ilaria ChiricoDepartment of Psychology, University of Bologna, Bologna, Italy.ORCID https://orcid.org/0000-0001-9799-0204
Rabih ChattatDepartment of Psychology, University of Bologna, Bologna, Italy.ORCID https://orcid.org/0000-0002-3889-2839
Anna Maria Della VedovaDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.ORCID https://orcid.org/0000-0002-3573-6451
Anna PecchinendaDepartment of Psychology, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0001-9139-5295
Maria CasagrandeDepartment of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0002-4430-3367

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extensive research indicates that cognitive interventions can lead to a general improvement in cognitive functioning throughout the lifespan. In this study, we evaluate the causal evidence supporting this relationship in healthy older adults and older adults with mild cognitive impairment (MCI) by means of an umbrella meta-analysis of meta-analyses. The meta-analytic studies were identified through systematic searches in electronic databases (CINAHL, Cochrane Library, PsycINFO, PubMed, Scopus, and Web of Science) and were included in this umbrella meta-analysis if they examined the effects of cognitive interventions, not mixed with other approaches, in healthy older adults and individuals with MCI. Of the 9734 publications that were screened, 25 met the inclusion criteria and reported comprehensive data suitable for statistical analysis. Findings showed that although the effect-sizes across studies were variable, they were consistently positive, indicating a significant impact of different cognitive interventions on global cognitive functioning, memory, executive functions, visuospatial ability, and processing speed compared to control groups. This finding suggests that the efficacy of cognitive treatments is the best option for preclinical forms of aging, such as MCI. The underlying mechanisms of the observed improvements and their implications for further studies and clinical practice are discussed.

Indexed as

cognitive interventionseffectivenesshealthy agingmild cognitive impairmentumbrella meta-analysis

Identifiers

PMID40552170
PMCPMC12185216

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.