Evidence mapPaperPMID 40552449Full record

ArticleDiabetes, obesity & metabolism2025

Real-world insights into incretin-based therapy: Associations between changes in taste perception and appetite regulation in individuals with obesity and overweight: A cross-sectional study.

Ali Kapan, Othmar Moser, Richard Felsinger, Thomas Waldhoer, Sandra Haider

Abstract read
In one paragraph

Article in Diabetes, obesity & metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ali KapanCenter for Public Health, Department of Social and Preventive Medicine, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-4007-0973
Othmar MoserDivision of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.ORCID https://orcid.org/0000-0002-1661-0685
Richard FelsingerCenter for Public Health, Department of Social and Preventive Medicine, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-7173-4218
Thomas WaldhoerCenter for Public Health, Department of Epidemiology, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0003-2043-8299
Sandra HaiderCenter for Public Health, Department of Social and Preventive Medicine, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-3612-7332

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis cross-sectional study examined associations between self-reported taste perception changes and appetite-related outcomes in individuals with obesity treated with glucagon-like peptide-1 receptor agonist (GLP-1 RAS) or dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 RAS in real-world conditions. MATERIALS AND

methodsFour hundred and eleven adults on Wegovy® (n = 217), Ozempic® (n = 148) and Mounjaro® (n = 46) completed an online survey assessing sociodemographic, anthropometric and sensory changes and appetite-related outcomes. Multivariable logistic regression was used to assess associations between taste changes and satiety, appetite and craving.

resultsParticipants (69.6% female; median age 39 [interquartile range, IQR 33-47]) had baseline body mass index (BMI) of 35.6 (Wegovy®), 34.7 (Ozempic®) and 36.2 kg/m

conclusionsSelf-reported changes in taste perception during GLP-1 or dual GIP/GLP-1 RAS therapy were associated with favourable appetite-related outcomes, suggesting a potential mechanism contributing to treatment response.

Indexed as

Appetite RegulationIncretinsObesityOverweightTaste PerceptionAdultBody Mass IndexCross-Sectional StudiesFemaleGastric Inhibitory PolypeptideGlucagon-Like Peptide-1 Receptor AgonistsHumansMaleMiddle AgedGastric Inhibitory PolypeptideGlucagon-Like Peptide-1 Receptor AgonistsIncretinsappetite regulationincretin‐based therapyobesity treatmentobservational studyweight management

Identifiers

PMID40552449
PMCPMC12326916

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.