Evidence mapPaperPMID 40554456Full record

ArticleAnalytical chemistry2025

Stable Isotope Labeling in Bacteria Enables Characterization and Quantification of Frataxin Protein in a Friedreich's Ataxia Zebrafish Model.

Teerapat Rojsajjakul, Wonwook Do, Robert B Wilson, Ian A Blair

Abstract read
In one paragraph

Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Teerapat RojsajjakulPenn/CHOP Friedreich's Ataxia Center of Excellence, Philadelphia, Pennsylvania 19104, United States.
Wonwook DoPenn/CHOP Friedreich's Ataxia Center of Excellence, Philadelphia, Pennsylvania 19104, United States.
Robert B WilsonPenn/CHOP Friedreich's Ataxia Center of Excellence, Philadelphia, Pennsylvania 19104, United States.
Ian A BlairPenn/CHOP Friedreich's Ataxia Center of Excellence, Philadelphia, Pennsylvania 19104, United States.ORCID 0000-0003-0366-8658

Funding

Translational Research Support CoreP30ES013508 · UNIVERSITY OF PENNSYLVANIA · 2025 to 2025
$1.6M
Elucidation of contributions of telomere damage and non-cell autonomy to the pathophysiology of Friedreich ataxia using a zebrafish modelR21NS133725 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI ROBERT B WILSON · 2023 to 2023
$494k
NIEHS NIH HHS P30 ES013508NINDS NIH HHS R21 NS133725NINDS NIH HHS U01 NS114143
6 · The paper itself

Abstract

Friedreich's ataxia (FRDA) is a neurodegenerative and cardiodegenerative genetic disorder caused primarily by homozygous mutations in the

Indexed as

Escherichia coliFriedreich AtaxiaIron-Binding ProteinsIsotope LabelingAnimalsChromatography, High Pressure LiquidDisease Models, AnimalFrataxinHumansMass SpectrometryZebrafishFrataxinIron-Binding Proteins

Identifiers

PMID40554456
PMCPMC12229242

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.