ArticleJournal of clinical periodontology2025
Characteristics of Subgingival Plaque Microbiome in Japanese Older Adults With Healthy Gingiva.
Article in Journal of clinical periodontology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Association between oral microbial diversity and periodontitis in a nationally representative U.S. population: A cross-sectional study.Journal of periodontology · 2026Article
- 16S rRNA analysis of proximal dental plaque bacteria reveals that daily use of commercialized disposable dental floss ItoyojiBMC oral health · 2026Article
- Characteristics of Subgingival Plaque Microbiome in Japanese Older Adults With Healthy Gingiva.Journal of clinical periodontology · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
aimTo elucidate the characteristics of the subgingival plaque microbiome in older adults without gingival inflammation. MATERIALS AND
methodsSubgingival plaque from 180 participants was collected and analysed using 16S rRNA sequencing. Based on the clinical parameters at the sampling sites, participants were categorised as healthy (gingival index [GI] = 0, maximum probing pocket depth [PPD
resultsWe observed differences in α-diversity and β-diversity between younger and older individuals only in the healthy group. Healthy older individuals showed a lower α-diversity index, indicating a healthy-like profile shift and also a significantly greater difference in β-diversity from the non-healthy group than the healthy younger subgroup. LEfSe analysis indicated that six amplicon sequence variants (ASVs), such as Rothia dentocariosa , Neisseria perflava and Actinomyces sp. HMT-448, were predominant in the healthy older subgroup.
conclusionMaintaining lower α-diversity, with an abundance of R. dentocariosa and N. perflava, which are possible nitrate-reducing bacteria, may contribute to lifelong healthy gingiva by preventing microbial dysbiosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.