Evidence mapPaperPMID 40556956Full record

ReviewFrontiers in physiology2025

Insulin resistance, Ca

Tatiana Romero-García, J Gustavo Vázquez-Jiménez, Rommel Sánchez-Hernández, J Alberto Olivares-Reyes, Angélica Rueda

Abstract readReview
In one paragraph

Review in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tatiana Romero-GarcíaDepartment of Biochemistry, Center for Research and Advanced Studies (Cinvestav) of the National Polytechnic Institute, México City, Mexico.
J Gustavo Vázquez-JiménezFacultad de Medicina, Universidad Autónoma de Baja California, Mexicali, Mexico.
Rommel Sánchez-HernándezDepartment of Biochemistry, Center for Research and Advanced Studies (Cinvestav) of the National Polytechnic Institute, México City, Mexico.
J Alberto Olivares-ReyesDepartment of Biochemistry, Center for Research and Advanced Studies (Cinvestav) of the National Polytechnic Institute, México City, Mexico.
Angélica RuedaDepartment of Biochemistry, Center for Research and Advanced Studies (Cinvestav) of the National Polytechnic Institute, México City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prediabetes and Metabolic Syndrome (MetS) share a common pathway to induce vascular dysfunction through hyperinsulinemia without the presence of overt hyperglycemia. Insulin resistance (IR) is a key factor in vascular complications in diabetes; however, vascular dysfunction has been reported in MetS patients, even in the absence of chronic hyperglycemic conditions. We consider that the alterations in the intracellular Ca

Indexed as

calcium signalingcalcium sparksinsulin signalingmetabolic syndromeprediabetesryanodine receptorsSERCA pumpvascular dysfunction

Identifiers

PMID40556956
PMCPMC12185281

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.