Evidence map›Paper›PMID 40557242›Full record

ArticleFrontiers in nutrition2025

Protocol: the International Milk Composition (IMiC) Consortium - a harmonized secondary analysis of human milk from four studies.

Kelsey Fehr, Andrew Mertens, Chi-Hung Shu, Trenton Dailey-Chwalibóg, Liat Shenhav, Lindsay H Allen, Megan R Beggs, Lars Bode, Rishma Chooniedass, Mark D DeBoer and 26 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05119166 (International Milk Composition), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05119166 active not recruitingnot on this map

International Milk Composition (IMiC) Consortium

TypeobservationalSponsorUniversity of ManitobaRan2019 to 2026Enrolled1,000ConditionsInfant Growth, Maternal Health, Infant NutritionArmsVitamin B3, Azithromycin, Fortified food supplement
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Artificial intelligence-guided nutritional therapy in the ICU.Current opinion in clinical nutrition and metabolic care · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Kelsey FehrDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.
Andrew MertensDivision of Epidemiology, School of Public Health, University of California Berkeley, Berkeley, CA, United States.
Chi-Hung ShuDepartment of Anesthesiology, Pain, and Perioperative Medicine, Stanford University School of Medicine, Stanford, CA, United States.
Trenton Dailey-ChwalibógDepartment of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Liat ShenhavInstitute for Systems Genetics, New York Grossman School of Medicine, New York University, New York, NY, United States.
Lindsay H AllenDepartment of Nutrition, University of California Davis, Davis, CA, United States.
Megan R BeggsTranslational Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
Lars BodeLarsson-Rosenquist Foundation Mother-Milk-Infant Center of Research Excellence, University of California San Diego, La Jolla, CA, United States.
Rishma ChooniedassSchool of Nursing, Faculty of Health and Social Development, University of British Columbia, Vancouver, BC, Canada.
Mark D DeBoerDepartment of Pediatrics, Division of Pediatric Endocrinology, University of Virginia School of Medicine, Charlottesville, VA, United States.
Lishi DengDepartment of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Camilo EspinosaDepartment of Anesthesiology, Pain, and Perioperative Medicine, Stanford University School of Medicine, Stanford, CA, United States.
Daniela HampelDepartment of Nutrition, University of California Davis, Davis, CA, United States.
April JahualInstitute for Systems Genetics, New York Grossman School of Medicine, New York University, New York, NY, United States.
Fyezah JehanDepartment of Paediatrics and Child Health Medical College, The Aga Khan University, Karachi, Pakistan.
Mohit JainSapient Bioanalytics, LLC, San Diego, CA, United States.
Patrick KolsterenDepartment of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Puja KawleCytel, Pune, India.
Kim A LagerborgSapient Bioanalytics, LLC, San Diego, CA, United States.
Melissa B ManusDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.
Samson MatarasoDepartment of Anesthesiology, Pain, and Perioperative Medicine, Stanford University School of Medicine, Stanford, CA, United States.
Joann M McDermidConsultant, Charlottesville, VA, United States.
Ameer MuhammadVaccines and Other Initiatives to Advance Lives (VITAL) Pakistan Trust, Karachi, Pakistan.
Payam PeymaniDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.
Martin PhamData Aggregation, Translation and Architecture (DATA) Team, University Health Network, Toronto, ON, Canada.
Setareh Shahab-FerdowsUnited States Department of Agriculture, Agricultural Research Service, Western Human Nutrition Research Center, Davis, Davis, CA, United States.
Yasir ShafiqCenter of Excellence for Trauma and Emergencies and Community Health Sciences, The Aga Khan University, Karachi, Pakistan.
Vishak SubramoneyDVPL Tech, Dubai, United Arab Emirates.
Daniel SunkoInstitute for Systems Genetics, New York Grossman School of Medicine, New York University, New York, NY, United States.
Laeticia Celine ToeDepartment of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Stuart E TurveyDepartment of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada.
Lei XueDepartment of Anesthesiology, Pain, and Perioperative Medicine, Stanford University School of Medicine, Stanford, CA, United States.
Natalie RodriguezDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.
Alan HubbardDivision of Epidemiology, School of Public Health, University of California Berkeley, Berkeley, CA, United States.
Nima AghaeepourDepartment of Anesthesiology, Pain, and Perioperative Medicine, Stanford University School of Medicine, Stanford, CA, United States.
Meghan B AzadDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Human milk (HM) contains a multitude of nutritive and nonnutritive bioactive compounds that support infant growth, immunity and development, yet its complex composition remains poorly understood. Integrating diverse scientific disciplines from nutrition and global health to data science, the International Milk Composition (IMiC) Consortium was established to undertake a comprehensive harmonized analysis of HM from low, middle and high-resource settings to inform novel strategies for supporting maternal-child nutrition and health. Methods and analysis: IMiC is a collaboration of HM experts, data scientists and four mother-infant health studies, each contributing a subset of participants: Canada (CHILD Cohort, Ethics and dissemination: IMiC was approved by the human research ethics board at the University of Manitoba. Contributing studies were approved by their respective primary institutions and local study centers, with all participants providing informed consent. Aiming to inform maternal, newborn, and infant nutritional recommendations and interventions, results will be disseminated through Open Access platforms, and data will be available for secondary analysis. Clinical trial registration: ClinicalTrials.gov, identifier, NCT05119166.

Indexed as

breastfeedinghuman milkinfant growthinfant nutritionmachine learning

Identifiers

PMID40557242
PMCPMC12186657

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.