Evidence map›Paper›PMID 40558167›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Use of Probiotics During Antibiotic Therapy in Pediatrics: A Cross-Sectional Survey of Italian Primary Care Pediatricians.

Giacomo Biasucci, Maria Elena Capra, Antonella Giudice, Delia Monopoli, Brigida Stanyevic, Roberta Rotondo, Alessandro Mucci, Cosimo Neglia, Beatrice Campana, Susanna Esposito

Registry-linked trialAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07234448 (Evaluation of the Use of a Probiotic Containing Bifidobacterium Breve PRL2020 in Oral Drops in Preventing Side Effects From Amoxicillin or Amoxicillin/Clavulanic Acid Antibiotic Use), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07234448 nacompletednot on this map

Evaluation of the Use of a Probiotic Containing Bifidobacterium Breve PRL2020 in Oral Drops in Preventing Side Effects From Amoxicillin or Amoxicillin/Clavulanic Acid Antibiotic Use: a Multicentre, Prospective, Randomized, Double-blind, Placebo-controlled Clinical Trial

TypeinterventionalSponsorLiaquat University of Medical & Health SciencesRan2025 to 2026Enrolled1,100ConditionsAntibiotic-associated DiarrheaArmsBrevicillin® gocce (Bifidobacterium breve PRL2020), Placebo (matching oil drops)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giacomo BiasucciPediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy.ORCID 0000-0002-7441-9248
Maria Elena CapraPediatrics and Neonatology Unit, Guglielmo da Saliceto Hospital, 29121 Piacenza, Italy.ORCID 0000-0003-0848-5228
Antonella GiudiceDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Delia MonopoliDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Brigida StanyevicDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Roberta RotondoDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Alessandro MucciDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Cosimo NegliaDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Beatrice CampanaDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Susanna EspositoDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0003-4103-2837

Funding

Next Generation EU I83C22001810007
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antibiotic-associated diarrheaantibioticsantimicrobial stewardshipmicrobiotaprobiotics

Identifiers

PMID40558167
PMCPMC12189294

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.