Evidence map›Paper›PMID 40558449›Full record

ArticleBiosensors2025

Influence of Gait Speed on Inter-Joint Coordination in People with and Without Parkinson's Disease.

Patrick Ippersiel, Philippe C Dixon, Elke Warmerdam, Robbin Romijnders, Walter Maetzler, Clint Hansen

Abstract read
In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Patrick IppersielCentre de Recherche Azrieli du CHU Sainte-Justine, Montreal, QC H3T 1C5, Canada.ORCID 0000-0001-6432-8118
Philippe C DixonDepartment of Kinesiology and Physical Activity, McGill University, 475 Av des Pins O 2nd Floor, Montreal, QC H2W 1S4, Canada.ORCID 0000-0003-3581-7259
Elke WarmerdamBiomedical Signals and Systems, Faculty of Electrical Engineering, Mathematics and Computer Science, University of Twente, 7522 Enschede, The Netherlands.
Robbin RomijndersDepartment of Neurology, University Hospital Schleswig-Holstein Campus Kiel, Kiel University, Arnold-Heller Str. 3, 24105 Kiel, Germany.ORCID 0000-0002-2507-0924
Walter MaetzlerDepartment of Neurology, University Hospital Schleswig-Holstein Campus Kiel, Kiel University, Arnold-Heller Str. 3, 24105 Kiel, Germany.ORCID 0000-0002-5945-4694
Clint HansenDepartment of Neurology, University Hospital Schleswig-Holstein Campus Kiel, Kiel University, Arnold-Heller Str. 3, 24105 Kiel, Germany.ORCID 0000-0003-4813-3868

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe influence of gait speed on lower-extremity coordination while walking in people with Parkinson's disease (pwPD) is poorly understood. This study sought to investigate the relationship between gait speed and hip-knee coordination and coordination variability in older adults and pwPD.

methodsA total of 27 pwPD and 21 healthy older adults were recruited. Participants walked in a straight line at slow, preferred, and fast walking speeds. Gait data were collected using inertial measurement units, and the kinematics of the hip and knee were calculated. Coordination and coordination variability at the hip-knee joint pair were determined using continuous relative phase. A repeated measures two-way ANCOVA tested the impact of gait speed on coordination and coordination variability, while group differences were evaluated using statistical parametric mapping (SPM).

resultsNeither the healthy older adults nor the pwPD adjusted their hip-knee coordination in response to changes in gait speed. pwPD also displayed a trend towards restricted hip and knee joint excursion compared to older adults, which may further limit their ability to adapt gait strategies.

conclusionsThese findings suggest that interventions addressing both joint excursion and motor adaptability may be important for improving gait function in individuals with Parkinson's disease. Real-world applicability can be found in the potential of wearable sensors to become a valuable tool in routine clinical practice for both diagnosis and ongoing management.

trial registrationThe study is registered in the German Clinical Trials Register (DRKS00022998).

Indexed as

GaitHip JointKnee JointParkinson DiseaseWalking SpeedAgedBiomechanical PhenomenaFemaleHumansMaleMiddle AgedWalkingcoordinationcoordination variabilitygait analysisinertial measurement unitsParkinson’s disease

Identifiers

PMID40558449
PMCPMC12190309

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.