Evidence map›Paper›PMID 40558484›Full record

ArticleCells2025

Characterization of Disseminated Tumor Cells (DTCs) in Patients with Triple-Negative Breast Cancer (TNBC).

Anne Eckardt, Ivonne Nel, Laura Weydandt, Elisa Brochwitz, Anne Kathrin Höhn, Karsten Winter, Bahriye Aktas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anne EckardtDepartment of Gynecology, Medical Center, Leipzig University, 04103 Leipzig, Germany.
Ivonne NelDepartment of Gynecology, Medical Center, Leipzig University, 04103 Leipzig, Germany.
Laura WeydandtDepartment of Gynecology, Medical Center, Leipzig University, 04103 Leipzig, Germany.ORCID 0000-0001-5216-3547
Elisa BrochwitzDepartment of Gynecology, Medical Center, Leipzig University, 04103 Leipzig, Germany.
Anne Kathrin HöhnDepartment of Pathology, Medical Center, Leipzig University, 04103 Leipzig, Germany.
Karsten WinterInstitute of Anatomy, Medical Faculty, Leipzig University, 04103 Leipzig, Germany.
Bahriye AktasDepartment of Gynecology, Medical Center, Leipzig University, 04103 Leipzig, Germany.ORCID 0000-0002-5474-051X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple negative breast cancer (TNBC) is the most aggressive molecular subtype and it lacks targetable receptors. Patients have an increased risk of recurrence and poor prognosis. Little is known concerning the characteristics of disseminated tumor cells (DTCs) and their role in TNBC patients. We analyzed the bone marrow aspirates of 80 patients with primary (

Indexed as

Neoplastic Cells, CirculatingTriple Negative Breast NeoplasmsAdultAgedB7-H1 AntigenBiomarkers, TumorCell ProliferationEpithelial-Mesenchymal TransitionErb-b2 Receptor Tyrosine KinasesFemaleHumansKi-67 AntigenMiddle AgedNeoplasm Recurrence, LocalPrognosisVimentinB7-H1 AntigenBiomarkers, TumorERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesKi-67 AntigenVimentinbone marrowbreast cancer (TNBC)disseminated tumor cells (DTCs)HER2Ki67neoadjuvant chemotherapypathologic complete remission (pCR)PD-L1triple negative

Identifiers

PMID40558484
PMCPMC12190861

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.