Evidence map›Paper›PMID 40558583›Full record

ArticleDiseases (Basel, Switzerland)2025

The Overlapping Burdens of Fatigue and Daytime Sleepiness: Gender-Specific Impacts on Life Quality in Patients with Sleep Disorders.

Bianca Temporini, Dario Bottignole, Giulia Balella, Giorgio Ughetti, Irene Pollara, Margherita Soglia, Francesco Rausa, Ylenia Ciuro, Christian Franceschini, Marcello Giuseppe Maggio and 2 more

Abstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Bianca TemporiniSleep Disorders Center, Department of Medicine and Surgery, Parma University Hospital, A. Gramsci Street 14, 43126 Parma, Italy.
Dario BottignoleSleep Disorders Center, Department of Medicine and Surgery, Parma University Hospital, A. Gramsci Street 14, 43126 Parma, Italy.ORCID 0009-0003-1986-8096
Giulia BalellaSleep Disorders Center, Department of Medicine and Surgery, Parma University Hospital, A. Gramsci Street 14, 43126 Parma, Italy.
Giorgio UghettiSleep Disorders Center, Department of Medicine and Surgery, Parma University Hospital, A. Gramsci Street 14, 43126 Parma, Italy.
Irene PollaraMario Giovanni Terzano Interdepartmental Centre for Sleep Medicine, University of Parma, A. Gramsci Street 14, 43126 Parma, Italy.ORCID 0009-0000-6253-7012
Margherita SogliaMario Giovanni Terzano Interdepartmental Centre for Sleep Medicine, University of Parma, A. Gramsci Street 14, 43126 Parma, Italy.
Francesco RausaSleep Disorders Center, Department of Medicine and Surgery, Parma University Hospital, A. Gramsci Street 14, 43126 Parma, Italy.
Ylenia CiuroSleep Disorders Center, Department of Medicine and Surgery, Parma University Hospital, A. Gramsci Street 14, 43126 Parma, Italy.
Christian FranceschiniMario Giovanni Terzano Interdepartmental Centre for Sleep Medicine, University of Parma, A. Gramsci Street 14, 43126 Parma, Italy.ORCID 0000-0002-9307-5209
Marcello Giuseppe MaggioMario Giovanni Terzano Interdepartmental Centre for Sleep Medicine, University of Parma, A. Gramsci Street 14, 43126 Parma, Italy.
Liborio ParrinoSleep Disorders Center, Department of Medicine and Surgery, Parma University Hospital, A. Gramsci Street 14, 43126 Parma, Italy.ORCID 0000-0002-4035-6234
Carlotta MuttiSleep Disorders Center, Department of Medicine and Surgery, Parma University Hospital, A. Gramsci Street 14, 43126 Parma, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExcessive daytime sleepiness (EDS) and fatigue are two impactful symptoms, frequently associated with sleep disorders, which can worsen the quality of life. Due to overlapping features and patient-report ambiguity a clear-cut distinction between EDS and fatigue can become a challenging issue. We aimed to investigate the prevalence and consequences of these two conditions in several sleep pathologies, examining their social, psychological, and dietary impact, with a focus on gender-related differences and occupational status.

methodsWe prospectively recruited for an online survey 136 adult outpatients (60 females) affected by various sleep disorders and admitted to our Sleep Disorders Center in Parma, Italy. Patients were asked to complete the following tests: Epworth Sleepiness Scale, Fatigue Severity Scale, Pittsburgh Sleep Quality Index, Difficulties in Emotion Regulation Scale, Depression Anxiety Stress Scale-21, Hyperarousal Scale, the Addiction-like Eating Behaviors Scale, Work Productivity and Activity Impairment Questionnaire, MEDI-Lite, and EQ-5D Health Questionnaire.

resultsFatigue was the primary daily symptom leading to serious repercussions on social/emotional and psychological well-being, while daytime sleepiness showed a less relevant role. Women reported higher levels of fatigue, sleep disturbances, emotional dysregulation, hyperarousal, and work productivity impairments. Unemployed people experienced a higher degree of fatigue, with multi-level negative consequences.

conclusionsWe suggest sleep clinicians place a greater emphasis on the assessment of fatigue during clinical interviews, keeping in mind the greater vulnerability of females, experiencing disproportionate consequences. Further studies should expand our findings, exploring a wider range of gender identities and recruiting larger samples of patients.

Indexed as

fatiguegender-related issuespsychological distresssleep disorderssleepiness

Identifiers

PMID40558583
PMCPMC12191932

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.