Evidence map›Paper›PMID 40558630›Full record

ArticleEuropean burn journal2025

Characterisation of Fluid Administration in Burn Shock-A Retrospective Cohort Analysis.

Marianne Kruse, Ida Katinka Lenz, David Josuttis, Philip Plettig, Klaus Hahnenkamp, Denis Gümbel, Claas Güthoff, Bernd Hartmann, Martin Aman, Marc Dominik Schmittner and 1 more

Abstract read
In one paragraph

Article in European burn journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marianne KruseDepartment of Anesthesiology, Intensive Care and Pain Medicine, BG-Klinikum Unfallkrankenhaus Berlin, 12683 Berlin, Germany.ORCID 0000-0001-6732-0920
Ida Katinka LenzDepartment of Anesthesiology, Intensive Care and Pain Medicine, BG-Klinikum Unfallkrankenhaus Berlin, 12683 Berlin, Germany.
David JosuttisDepartment of Anesthesiology, Intensive Care and Pain Medicine, BG-Klinikum Unfallkrankenhaus Berlin, 12683 Berlin, Germany.ORCID 0000-0001-9086-9065
Philip PlettigDepartment of Anesthesiology, Intensive Care and Pain Medicine, BG-Klinikum Unfallkrankenhaus Berlin, 12683 Berlin, Germany.ORCID 0000-0002-8314-7985
Klaus HahnenkampDepartment of Anesthesiology, University Medicine Greifswald, 17475 Greifswald, Germany.
Denis GümbelDepartment of Orthopedics, Trauma Surgery and Rehabilitative Medicine, University Medicine Greifswald, 17471 Greifswald, Germany.ORCID 0000-0003-1330-2676
Claas GüthoffCenter for Clinical Research, BG Klinikum Unfallkrankenhaus Berlin gGmbH, 12683 Berlin, Germany.ORCID 0000-0002-9984-6908
Bernd HartmannBurn Center, Department of Plastic Surgery, BG Klinikum Unfallkrankenhaus Berlin, 12683 Berlin, Germany.
Martin AmanClinic for Hand, Replantation, and Microsurgery BG Klinikum Unfallkrankenhaus Berlin and Chair of Hand, Replantation, and Microsurgery at the Charité University Medicine Berlin, 10117 Berlin, Germany.
Marc Dominik SchmittnerDepartment of Anesthesiology, Intensive Care and Pain Medicine, BG-Klinikum Unfallkrankenhaus Berlin, 12683 Berlin, Germany.ORCID 0000-0003-3947-8370
Volker GebhardtDepartment of Anesthesiology, Intensive Care and Pain Medicine, BG-Klinikum Unfallkrankenhaus Berlin, 12683 Berlin, Germany.ORCID 0000-0001-7689-5267

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFinding the optimal amount of fluid is a major challenge in burn shock. Although there is evidence that a restrictive fluid regime is beneficial, current practice shows fluid resuscitation still well above recommendations. The extent of trauma, pre-hospital care and the patient's pre-existing conditions influence requirements.

methodsWe analysed outcomes and influencing factors of fluid regimes in a retrospective cohort study including 90 severely burnt patients resuscitated with the same protocol.

resultsThe mean amount of fluids in the first 24 h was 6.5 mL/kg bodyweight (BW)/% total burn surface area (TBSA). A total of 14% received restrictive (<4), 34% received liberal (4-6) and 51% received excessive (>6) mL/kgBW/%TBSA fluids. There was no difference regarding mortality, age, complications, organ failure, inhalation injury or full-thickness burns in the groups. Patients with excessive fluid therapy had a significantly lower ABSI score (9 vs. 11,

conclusionsIndividualised, timely therapy monitoring is as essential as identifying patients with a higher or lower fluid requirement. Excessive fluid resuscitation had fewer deleterious consequences in complications than expected but seems to influence wound healing. Awareness of circumstances that prompt deviations from recommended fluid rates remains elementary.

Indexed as

burn shockfluid creepfluid resuscitationsevere burn injury

Identifiers

PMID40558630
PMCPMC12191774

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.