Evidence map›Paper›PMID 40558651›Full record

ArticleJournal of cardiovascular development and disease2025

The Efficacy and Safety of Outpatient Exercise Training for Patients with Chronic Thromboembolic Pulmonary Hypertension After Balloon Pulmonary Angioplasty.

Takayuki Masuda, Keitaro Akita, Ryota Sato, Takenori Ikoma, Yusuke Mizuno, Terumori Satoh, Masashi Takao, Kenichiro Suwa, Mikihiro Shimizu, Keiichi Odagiri and 2 more

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Takayuki MasudaDepartment of Rehabilitation Medicine, Hamamatsu University Hospital, 1-20-1 Handayama, Chuo-ku, Hamamatsu 431-3192, Japan.
Keitaro AkitaDivision of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu 431-3192, Japan.ORCID 0000-0001-5395-1887
Ryota SatoDivision of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu 431-3192, Japan.
Takenori IkomaDivision of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu 431-3192, Japan.
Yusuke MizunoDivision of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu 431-3192, Japan.
Terumori SatohDivision of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu 431-3192, Japan.
Masashi TakaoDepartment of Rehabilitation Medicine, Hamamatsu University Hospital, 1-20-1 Handayama, Chuo-ku, Hamamatsu 431-3192, Japan.
Kenichiro SuwaDivision of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu 431-3192, Japan.ORCID 0000-0001-6934-7932
Mikihiro ShimizuCenter for Clinical Research, Hamamatsu University Hospital, 1-20-1 Handayama, Chuo-ku, Hamamatsu 431-3192, Japan.
Keiichi OdagiriCenter for Clinical Research, Hamamatsu University Hospital, 1-20-1 Handayama, Chuo-ku, Hamamatsu 431-3192, Japan.ORCID 0000-0001-6968-0516
Katsuya YamauchiDepartment of Rehabilitation Medicine, Hamamatsu University Hospital, 1-20-1 Handayama, Chuo-ku, Hamamatsu 431-3192, Japan.
Yuichiro MaekawaDivision of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu 431-3192, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the efficacy and safety of outpatient exercise training in clinically stabilized patients with chronic thromboembolic pulmonary hypertension (CTEPH) after balloon pulmonary angioplasty (BPA).

methodsTwenty-four patients with CTEPH after BPA were enrolled in this prospective single-center study. Patients were assigned to the exercise and control groups. The exercise group comprised 12 patients who received 15 weeks of exercise training, with usual care. The control group received only the usual care, without exercise training. The exercise program included aerobic exercise thrice weekly and resistance exercise once or twice weekly. The assessments employed included a 6-min walk test, cardiopulmonary exercise testing, and an emPHasis-10 questionnaire.

resultsIn the exercise group, the 6-min walk distance was significantly longer (510.0 [467.5, 595.0] m vs. 425.0 [395.0, 465.0] m,

conclusionsExercise training improved gait performance, without any adverse events, in patients with CTEPH after BPA. Therefore, exercise training as an adjunct to medical therapy may be a safe potential therapy for patients with CTEPH after BPA.

Indexed as

exercise traininggait performancequality of liferehabilitation

Identifiers

PMID40558651
PMCPMC12194410

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.