Evidence map›Paper›PMID 40558721›Full record

ReviewGels (Basel, Switzerland)2025

Advances in 3D Bioprinting for Corneal Regeneration.

Juan Hernández, Nicolás Santos, Manuel Ahumada

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Juan HernándezEscuela de Tecnología Médica, Facultad de Ciencias de la Vida, Universidad Viña del Mar, Viña del Mar 2572007, Chile.ORCID 0000-0001-6529-2866
Nicolás SantosInstitut Químic de Sarrià, Universitat Ramon Llull, 08017 Barcelona, Spain.ORCID 0009-0004-1226-2195
Manuel AhumadaCentro de Nanotecnología Aplicada, Facultad de Ciencias, Ingeniería y Tecnología, Universidad Mayor, Santiago 8580745, Chile.ORCID 0000-0002-0589-3296

Funding

Agencia Nacional de Investigación y Desarrollo FONDECYT 1241229
6 · The paper itself

Abstract

Worldwide, millions of people suffer from visual impairments, ranging from partial to total blindness, with far-reaching consequences on personal, societal, and governmental levels. Corneal-related issues are among the leading causes of blindness, with corneal transplantation (keratoplasty) being the primary treatment. However, the demand for donor tissues far exceeds supply. The rise of printing technologies marks a revolution in tissue engineering, with 3D bioprinting at the forefront of developing innovative tissue repair and replacement solutions. The cornea emerges as an ideal candidate for this technology due to its distinct layers (epithelium, stroma, and endothelium). From a materials engineering standpoint, these layers resemble a hydrogel structure that facilitates fabrication. This review explores advancements in 3D bioprinting, focusing on the methodologies developed for corneal tissue engineering. It highlights design and construction aspects, including biomechanical and biocompatibility properties essential for creating synthetic implants and corneal scaffolds through bioprinting. Additionally, the review discusses the challenges and opportunities that could further drive innovation in tissue engineering.

Indexed as

biocompatible materialsbioprintingcorneacorneal transplantationtissue engineering

Identifiers

PMID40558721
PMCPMC12192301

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.