Evidence map›Paper›PMID 40559196›Full record

ArticleInfectious disease reports2025

Differential Effects of Human Immunodeficiency Virus Nef Variants on Pulmonary Vascular Endothelial Cell Dysfunction.

Amanda K Garcia, Noelia C Lujea, Javaria Baig, Eli Heath, Minh T Nguyen, Mario Rodriguez, Preston Campbell, Isabel Castro Piedras, Edu Suarez Martinez, Sharilyn Almodovar

Abstract read
In one paragraph

Article in Infectious disease reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amanda K GarciaDepartment of Immunology & Molecular Microbiology, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Noelia C LujeaDepartment of Immunology & Molecular Microbiology, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.ORCID 0000-0001-7293-7343
Javaria BaigDepartment of Immunology & Molecular Microbiology, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Eli HeathDepartment of Chemical Engineering, Edward E. Whitacre Jr. College of Engineering, Texas Tech University, Lubbock, TX 79430, USA.ORCID 0009-0000-0235-8127
Minh T NguyenCollege of Arts and Sciences, Texas Tech University, Lubbock, TX 79430, USA.
Mario RodriguezCenter for Biotechnology & Genomics, Texas Tech University, Lubbock, TX 79430, USA.
Preston CampbellCollege of Arts and Sciences, Texas Tech University, Lubbock, TX 79430, USA.
Isabel Castro PiedrasCenter for Biotechnology & Genomics, Texas Tech University, Lubbock, TX 79430, USA.
Edu Suarez MartinezDepartment of Biology, University of Puerto Rico at Ponce, Ponce, PR 00732, USA.ORCID 0000-0002-6050-7570
Sharilyn AlmodovarDepartment of Immunology & Molecular Microbiology, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.ORCID 0000-0002-4769-1924

Funding

Role of HIV gp120 and Nef in Transcriptome Dysregulation and Pulmonary Vascular RemodelingR01HL172709 · NHLBI · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI SHARILYN ALMODOVAR · 2024 to 2026
$2.1M
Investigating Novel HIV Reservoirs in the Pulmonary VasculatureR21AI181657 · NIAID · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI ALMODOVAR, SHARILYN · 2024 to 2025
$395k
NHLBI NIH HHS R01 HL172709NIAID NIH HHS R21 AI181657NIH HHS 1R01HL172709-01S1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

apoptosisendothelial cell dysfunctionendothelin-1eNOSE-selectinHIV NefHIV proteinsICAM1inflammationpulmonary vascular cell co-culturepulmonary vascular remodelingVCAM1

Identifiers

PMID40559196
PMCPMC12193658

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.