Evidence map›Paper›PMID 40559657›Full record

ArticleMarine drugs2025

Evaluation of the Immunostimulatory Effect of Ulvan Polysaccharide on Human Macrophages: Use as a Potential Vaccine Adjuvant.

Valeska Guevara-Torrejón, Paola Chandía Parra, Carolina Campos-Estrada, Waleska E Vera Quezada

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Valeska Guevara-TorrejónLaboratorio de Química de Metabolitos Bioactivos, Facultad de Farmacia, Universidad de Valparaíso, Valparaíso 2340000, Chile.
Paola Chandía ParraLaboratorio de Moléculas Bioactivas, Facultad de Ciencias del Mar, Universidad Católica del Norte, Coquimbo 1780000, Chile.
Carolina Campos-EstradaLaboratorio Toxicología, Facultad de Farmacia, Universidad de Valparaíso, Valparaíso 2340000, Chile.
Waleska E Vera QuezadaLaboratorio de Química de Metabolitos Bioactivos, Facultad de Farmacia, Universidad de Valparaíso, Valparaíso 2340000, Chile.ORCID 0000-0002-9965-9563

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ulvans are sulfated heteropolysaccharides that can stimulate the immune response in vitro. Using a human cell model, this study aimed to characterize and evaluate the immunostimulatory properties of crude ulvans extracted from

Indexed as

Adjuvants, ImmunologicAdjuvants, VaccineMacrophagesPolysaccharidesUlvaCell SurvivalCytokinesHumansNitric OxideAdjuvants, ImmunologicAdjuvants, VaccineCytokinesNitric OxidePolysaccharidesulvanadjuvantimmunostimulantsulphated polysaccharidesulvanvaccines

Identifiers

PMID40559657
PMCPMC12194736

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.