Evidence map›Paper›PMID 40559658›Full record

ArticleMarine drugs2025

Microwave Pretreatment-Induced Significant Nutrient and Metabolite Changes in Sea Cucumber

Dairong Song, Fang Liu, Airong Jia, Xue Liu, Tingting Cui, Hui Zhang, Miansong Zhang

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dairong SongBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Fang LiuBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Airong JiaBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Xue LiuBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Tingting CuiBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.ORCID 0000-0001-6685-9457
Hui ZhangBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Miansong ZhangBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.ORCID 0000-0001-5748-573X

Funding

Department of Science & Technology of Shandong Province 2021TZXD008Department of Science & Technology of Shandong Province 2022TSGC1306Pilot Project for the Integration of Education, Science and Industry Innovation of Qilu University of Technology (Shandong Academy of Sciences) 2024GH02Qilu University of Technology (Shandong Academy of Sciences) 2022JBZ01-06
6 · The paper itself

Abstract

The body wall of sea cucumbers is rich in nutrients and small-molecule metabolites; however, traditional hot water pretreatment often leads to nutrient loss. To optimise processing techniques, this study compared the effects of microwave pretreatment and conventional hot water pretreatment on nutrient retention and metabolite profiles. Untreated sea cucumber body wall samples served as controls. The samples were subjected to microwave pretreatment (4 W/g, 12 min) or hot water pretreatment (100 °C, 10 min). Nutrient retention rates and metabolite variations were systematically analysed. Microwave pretreatment demonstrated superior retention of protein (96%), crude fat (92%), total sugar (55%), and saponins (40%). It also promotes the accumulation of small-molecule metabolites, including spermidine, tagatose, and melatonin. Notably, the lysine and methionine retention rates were enhanced by 10-fold and 12-fold, respectively, while the vitamin A, vitamin B3, and melatonin retention increased by 2.4-fold, 2-fold, and 3-fold, significantly outperforming traditional pretreatment. These findings highlight the potential of microwave pretreatment as an efficient alternative to conventional methods for preserving the nutritional and functional components of sea cucumbers.

Indexed as

MicrowavesNutrientsSea CucumbersStichopusAnimalsMelatoninMelatoninNutrientsApostichopus japonicusmetabolite profilemicrowave pretreatmentnon-targeted metabolomics analysis

Identifiers

PMID40559658
PMCPMC12194430

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.