Evidence map›Paper›PMID 40560334›Full record

ArticleThe international journal of cardiovascular imaging2025

Left atrial and ventricular strain and extracellular volume fraction in patients with paroxysmal and persistent atrial fibrillation.

Masafumi Takafuji, Masaki Ishida, Yoshihiko Kagawa, Satoshi Fujita, Shintaro Yamaguchi, Satoshi Nakamura, Haruno Ito, Takanori Kokawa, Suguru Araki, Kakuya Kitagawa and 2 more

Abstract read
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Article in The international journal of cardiovascular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Masafumi TakafujiDepartment of Radiology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Masaki IshidaDepartment of Radiology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. ishidamasaki1@gmail.com.
Yoshihiko KagawaDepartment of Cardiology and Nephrology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Satoshi FujitaDepartment of Cardiology and Nephrology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Shintaro YamaguchiDepartment of Radiology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Satoshi NakamuraDepartment of Radiology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Haruno ItoDepartment of Radiology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Takanori KokawaDepartment of Radiology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Suguru ArakiDepartment of Radiology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Kakuya KitagawaDepartment of Radiology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Kaoru DohiDepartment of Cardiology and Nephrology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Hajime SakumaDepartment of Radiology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.

Funding

Japan Society for the Promotion of Science 18K07749 and 24K10807
6 · The paper itself

Abstract

To investigate cardiac MR (CMR) parameters, including left atrial (LA)/left ventricular (LV) volume, function, and extracellular volume fraction (ECV), in persistent and paroxysmal AF after catheter ablation and to evaluate the relationship between ECV and CMR parameters in AF patients. Participants comprised 41 patients with AF (persistent AF, n = 25; paroxysmal AF, n = 16) who underwent CMR study including cine-CMR, late gadolinium enhancement (LGE) CMR, and pre- and post-contrast T1 mapping within a week after restoration of sinus rhythm by catheter ablation and 18 matched controls. LA/LV volume and function and LV-ECV were determined by cine-CMR and T1 mapping, respectively. LA reservoir, conduit, and contractile strains (εR, εCD, and εCT) were determined by feature tracking. LV-ECV in patients with persistent AF (29.6 ± 3.2%) was significantly higher than that in controls (27.0 ± 1.9%, p < 0.01), and no significant differences were seen in ECV between the patients with persistent AF and paroxysmal AF and between patients with paroxysmal AF and controls. In patients with AF, univariate linear regression analyses showed that ECV correlated significantly with LV end-systolic volume index (ESVI) (p = 0.03), εR (p = 0.01), and εCD (p = 0.005). Stepwise multivariate analysis, including LV ESVI, εR and εCD as variables, revealed that εCD was independently associated with ECV (standardized β = -0.39, p = 0.009). Patients with persistent AF had higher LV-ECV than controls. LA εCD was independently associated with increased ECV in patients with AF. These results suggest advanced LV fibrosis in patients with persistent AF and that CMR LA strain analysis can predict the severity of LV fibrosis in patients with AF.

Indexed as

Atrial FibrillationAtrial Function, LeftAtrial RemodelingHeart AtriaMagnetic Resonance Imaging, CineVentricular Function, LeftAgedBiomechanical PhenomenaCase-Control StudiesCatheter AblationContrast MediaFemaleFibrosisHumansMaleMiddle AgedContrast MediaAtrial fibrillationConduit strainContractile strainExtracellular volume fractionFeature trackingReservoir strain

Identifiers

PMID40560334

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.