Evidence map›Paper›PMID 40560801›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2025

Sugar type and route of delivery influence insulin and glucose-dependent insulinotropic polypeptide responses in rats.

A Valentina Nisi, Myrtha M L Arnold, Ginger D Blonde, Lindsey A Schier, Graciela Sanchez-Watts, Alan G Watts, Wolfgang Langhans, Alan C Spector

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

A Valentina NisiDepartment of Psychology and Program in Neuroscience, Florida State University, Tallahassee, Florida, United States.
Myrtha M L ArnoldPhysiology and Behavior Laboratory, ETH Zurich, Schwerzenbach, Switzerland.
Ginger D BlondeDepartment of Psychology and Program in Neuroscience, Florida State University, Tallahassee, Florida, United States.
Lindsey A SchierDepartment of Biological Sciences, University of Southern California, Los Angeles, California, United States.
Graciela Sanchez-WattsDepartment of Biological Sciences, University of Southern California, Los Angeles, California, United States.
Alan G WattsDepartment of Biological Sciences, University of Southern California, Los Angeles, California, United States.ORCID 0000-0002-0942-4921
Wolfgang LanghansPhysiology and Behavior Laboratory, ETH Zurich, Schwerzenbach, Switzerland.ORCID 0000-0001-9742-0068
Alan C SpectorDepartment of Psychology and Program in Neuroscience, Florida State University, Tallahassee, Florida, United States.ORCID 0000-0001-6817-6334

Funding

Neural Bases of Cephalic Phase Endocrine ResponsesR01DK118910 · NIDDK · FLORIDA STATE UNIVERSITY · PI Alan C Spector, Alan G Watts · 2023 to 2023
$596k
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01-DK118910NIDDK NIH HHS R01 DK118910
6 · The paper itself

Abstract

To help resolve the characteristics of orally stimulated endocrine responses to sugar, we developed a novel rat preparation with surgically implanted intraoral (IO) and intragastric (IG) cannulas for stimulus delivery, along with jugular vein catheters for blood sampling, and tested the effects of 1-min and 10-min IO versus IG infusions (1 mL/min) of 1.0 M glucose on plasma levels of insulin, glucose-dependent insulinotropic polypeptide (GIP), and glucose. Oral glucose delivery (1 min and 10 mins) caused a greater (

Indexed as

FructoseGastric Inhibitory PolypeptideGlucoseInsulinAdministration, OralAnimalsBlood GlucoseMaleRatsRats, Sprague-DawleyBlood GlucoseFructoseGastric Inhibitory PolypeptideGlucoseInsulincephalic phase insulin releaseGIPglucoseglucose sensingmetabolism

Identifiers

PMID40560801
PMCPMC12320374

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.