ReviewThe Journal of international medical research2025
The role and mechanism of human papillomavirus in urinary system tumors.
Review in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Based on the level of carcinogenic risk, human papillomavirus can be categorized into high-risk and low-risk types. High-risk human papillomavirus (such as human papillomavirus 16 and human papillomavirus 18) induces the inactivation of tumor suppressor genes p53 and retinoblastoma by encoding E6 and E7 proteins, leading to dysregulated cell cycles and excessive cell proliferation. In urothelial tumors, human papillomavirus infection is associated with the occurrence and progression of bladder cancer, playing a significant role in urothelial tumor development. This may be linked to specific molecular mechanisms triggered by human papillomavirus and its impact on treatment response. Furthermore, high expression of human papillomavirus-related molecular markers, such as p16, can serve as an important tool for predicting and monitoring the prognosis of human papillomavirus-associated tumors. Therefore, detecting and monitoring human papillomavirus infection status and related molecular markers can provide a more accurate assessment of bladder cancer prognosis and offer valuable guidance for formulating personalized treatment plans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.