ReviewBiomedicines2025
Regulatory Genetic Networks by microRNAs: Exploring Genomic Signatures in Cervical Cancer.
Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- miR-4687-3p modulates cell proliferation and migration in cervical cancer cells.Molecular biology reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Cervical cancer remains a significant global health concern, impacting over half a million women annually. The primary cause is a persistent infection with hr-HPV, which disrupts various cellular processes crucial for normal function. This disruption leads to genetic instability, including changes in the expression of microRNAs and their corresponding host genes, with far-reaching consequences for cellular regulation. Researchers have widely utilized high-throughput technologies to analyze gene expression in cervical cancer, aiming to identify distinct molecular signatures of microRNAs and genes through genomic analysis. However, discrepancies among studies have been noted, possibly due to variations in sample collection, technological platforms, and data processing methods such as normalization and filtering. Therefore, it is essential to synthesize findings from diverse studies to comprehensively understand the molecular mechanisms of regulatory genetic networks involved in the initiation and progression of cervical cancer. This review examined the evidence detailing the role of microRNA signatures and their target genes in cervical carcinogenesis and disease advancement. The accumulated data suggest the presence of widespread regulatory genetic networks active in both precancerous and cancerous cervical cells, potentially acting as key drivers of this malignancy. Identifying these molecular genomic signatures could open new avenues for developing therapeutic strategies for cervical cancer, particularly in the realm of precision medicine.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.