Evidence mapPaperPMID 40564468Full record

ReviewBioengineering (Basel, Switzerland)2025

The Risks Associated with Inhalation Exposure to Cosmetics and Potential for Assessment Using Lung Organoids.

Yiguang Li, Xin Luo, Rong Hu, Lifeng Tang, Qi Xiang

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yiguang LiState Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou 510632, China.
Xin LuoBiopharmaceutical R&D Center of Jinan University Co., Ltd., Guangzhou 510632, China.
Rong HuHBN Research Institute and Biological Laboratory, Shenzhen Hujia Technology Co., Ltd., Shenzhen 510663, China.
Lifeng TangGuangzhou Xika Technology Co., Ltd., Guangzhou 510330, China.
Qi XiangState Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou 510632, China.ORCID 0000-0001-9790-5823

Funding

Guangzhou city school union, China 2024A03J0821Natural Science Foundation of Guangdong Province, China 2021A1515012480R&D Plan Project in Key Fields of Guangdong Province, China 2022B1111080007the National Key Research and Development Program of China 2022YFC2403102
6 · The paper itself

Abstract

This review addresses the exposure risks associated with the inhalation of aerosolized cosmetic products and explores the utility of lung organoids in assessing these risks. Aerosolized cosmetics such as sprays pose potential health hazards through inhalation, necessitating a thorough evaluation of exposure levels. Traditional methods for assessing inhalation risks have limitations, prompting the exploration of more sophisticated models. Lung organoids, three-dimensional structures derived from stem cells, offer a biologically relevant model for studying lung responses to inhaled substances. This review discusses the construction of lung organoids, their characteristics, and the advantages that they provide over conventional models. Furthermore, it examines existing studies that have employed lung organoids to evaluate the effects of cosmetic inhalation exposure, highlighting the potential of this approach to enhance the safety assessments of cosmetic products. We aim to establish lung organoids as a reliable tool for future research, ensuring the safety and regulatory compliance of cosmetics.

Indexed as

cosmeticsinhalation exposurelung organoidsrisk assessment

Identifiers

PMID40564468
PMCPMC12189234

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.