Evidence map›Paper›PMID 40564906›Full record

ArticleInternational journal of molecular sciences2025

Swt21p Is Required for Nam8p-U1 snRNP Association and Efficient Pre-mRNA Splicing in

Ke Lin, Xiuhu Fu, Lulu Wang, Sa Xiao, Shenxin Wang, Yingjie Fan, Xinyu An, Kum-Loong Boon, Penghui Bao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ke LinInstitute of Molecular Enzymology, School of Life Sciences, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Xiuhu FuInstitute of Molecular Enzymology, School of Life Sciences, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Lulu WangInstitute of Molecular Enzymology, School of Life Sciences, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Sa XiaoInstitute of Molecular Enzymology, School of Life Sciences, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Shenxin WangInstitute of Molecular Enzymology, School of Life Sciences, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Yingjie FanInstitute of Molecular Enzymology, School of Life Sciences, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Xinyu AnInstitute of Molecular Enzymology, School of Life Sciences, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Kum-Loong BoonInstitute of Molecular Enzymology, School of Life Sciences, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Penghui BaoInstitute of Molecular Enzymology, School of Life Sciences, Suzhou Medical College of Soochow University, Suzhou 215123, China.ORCID 0000-0001-8259-2334

Funding

Soochow University Q413400320, NH13400222 and NH13400623
6 · The paper itself

Abstract

While the U1 small nuclear ribonucleoprotein (snRNP) plays a crucial role in early spliceosome assembly, the mechanisms by which it coordinates with other splicing factors for efficient assembly remain elusive. This study aimed to examine the role of the Swt21 protein in regulating U1 snRNP in

Indexed as

Ribonucleoprotein, U1 Small NuclearRNA-Binding ProteinsRNA PrecursorsRNA SplicingSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsProtein BindingSpliceosomesRibonucleoprotein, U1 Small NuclearRNA-Binding ProteinsRNA PrecursorsSaccharomyces cerevisiae ProteinsNam8ppre-mRNA splicingspliceosome assemblySwt21pU1 snRNP

Identifiers

PMID40564906
PMCPMC12192654

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.