Evidence map›Paper›PMID 40564991›Full record

ReviewInternational journal of molecular sciences2025

Understanding the Role of Endocannabinoids in Posttraumatic Stress Disorder.

Luke Ney

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Luke NeySchool of Psychology and Counselling, Queensland University of Technology, Brisbane 4059, Australia.

Funding

National Health and Medical Research Council GNT2017125
6 · The paper itself

Abstract

Posttraumatic stress disorder is often treatment-resistant and recent research has suggested that treatment outcomes might be improved by modulation of the endocannabinoid system. The current review article describes animal and human research examining the effect of endocannabinoid modulation on posttraumatic symptoms, behaviours, and relevant memory processes. While the preclinical literature is reasonably consistent, emerging human literature is mixed. This review explores some potential reasons for why human research in this field is inconsistent and proposes multiple avenues for future research to answer these questions. Clinical trials testing the logistical challenges of cannabinoid administration and carefully designed human experimental studies are urgently required before cannabinoid therapy can be considered as an approach for treatment of posttraumatic stress disorder.

Indexed as

EndocannabinoidsStress Disorders, Post-TraumaticAnimalsCannabinoidsHumansReceptors, CannabinoidCannabinoidsEndocannabinoidsReceptors, Cannabinoidcannabinoidscannabisendocannabinoidsposttraumatic stress disorderPTSD

Identifiers

PMID40564991
PMCPMC12192862

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.