Evidence map›Paper›PMID 40565352›Full record

SynthesisInternational journal of molecular sciences2025

Comparison of the Mediterranean Diet and Other Therapeutic Strategies in Metabolic Syndrome: A Systematic Review and Meta-Analysis.

Alejandro Bruna-Mejias, Jessica San Martin, Danna Arciniegas-Diaz, Trinidad Meneses-Caroca, Amelia Salamanca-Cerda, Antonia Beas-Gambi, Jessica Paola-Loaiza-Giraldo, Cynthia Ortiz-Ahumada, Pablo Nova-Baeza, Gustavo Oyanedel-Amaro and 4 more

Abstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alejandro Bruna-MejiasDepartamento de Ciencias y Geografía, Facultad de Ciencias Naturales y Exactas, Universidad de Playa Ancha, Valparaíso 2360072, Chile.
Jessica San MartinDepartamento de Morfología, Facultad de Medicina, Universidad Andrés Bello, Santiago 8370146, Chile.
Danna Arciniegas-DiazDepartamento de Morfología, Facultad de Medicina, Universidad Andrés Bello, Santiago 8370146, Chile.
Trinidad Meneses-CarocaDepartamento de Morfología, Facultad de Medicina, Universidad Andrés Bello, Santiago 8370146, Chile.
Amelia Salamanca-CerdaDepartamento de Morfología, Facultad de Medicina, Universidad Andrés Bello, Santiago 8370146, Chile.
Antonia Beas-GambiDepartamento de Morfología, Facultad de Medicina, Universidad Andrés Bello, Santiago 8370146, Chile.
Jessica Paola-Loaiza-GiraldoFacultad de Ciencias de la Salud, Unidad Central del Valle del Cauca (UCEVA), Tuluá 763022, Valle del Cauca, Colombia.ORCID 0000-0002-6582-4153
Cynthia Ortiz-AhumadaDepartamento de Morfología, Facultad de Medicina, Universidad Andrés Bello, Santiago 8370146, Chile.
Pablo Nova-BaezaDepartamento de Morfología, Facultad de Medicina, Universidad Andrés Bello, Santiago 8370146, Chile.ORCID 0000-0003-0098-0224
Gustavo Oyanedel-AmaroFacultad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago 7500912, Chile.
Mathias Orellana-DonosoEscuela de Medicina, Universidad Finis Terrae, Santiago 7501015, Chile.ORCID 0000-0002-1781-062X
Alejandra Suazo-SantibáñezFaculty of Health and Social Sciences, Universidad de Las Américas, Santiago 8370040, Chile.
Juan Sanchis-GimenoGIAVAL Research Group, Department of Anatomy and Human Embryology, Faculty of Medicine, University of Valencia, 46001 Valencia, Spain.ORCID 0000-0002-2599-8474
Juan José Valenzuela-FuenzalidaDepartamento de Morfología, Facultad de Medicina, Universidad Andrés Bello, Santiago 8370146, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Mediterranean diet (MD) is one of the healthiest diets, high in fiber, antioxidants, and unsaturated fats. MD improves lipid profiles, reduces inflammation, controls blood pressure, decreases insulin resistance, and enhances the sensitivity to this hormone, lowering the risks of Metabolic syndrome (MS). MS is characterized by central obesity, hypertension, insulin resistance, and dyslipidemia, increasing the risk of cardiovascular disease and type II diabetes. The objective of this study was to know the effectiveness of the MD versus other treatments in patients with MS. A systematic search across multiple databases, Medline, Embase, Web of Science, Scopus, Google Scholar, and Cinahl, was conducted using keywords such as "Mediterranean diet", "Mediterranean food", "eat mediterranean", "Metabolic syndrome", and "x syndrome". A total of 12 studies met the inclusion criteria. Mediterranean diet at different doses versus other diets or other treatments showed significant improvements in clinical parameters, including BMI (mean difference of -0.83 95% CI: -0.93 to -0.74;

Indexed as

Diet, MediterraneanMetabolic SyndromeHumansInsulin Resistanceeat mediterraneanmediterranean dietmediterranean foodmetabolic syndromex syndrome

Identifiers

PMID40565352
PMCPMC12192665

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.