Evidence map›Paper›PMID 40566347›Full record

SynthesisInternational journal of environmental research and public health2025

A Systematic Review of Cardiovascular Health Among Cancer Survivors.

Miriam A Miles, Oluseun Akinyele, Abigail A Ninson, Nicole Caviness-Ashe, Cha'Breia Means, Le'Andrea Anderson-Tolbert, Tuchondriana Smith, Reagan Coleman, Laura Q Rogers, Joshua J Joseph and 2 more

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Miriam A MilesDepartment of Medicine, Division of General Internal Medicine and Population Science, University of Alabama at Birmingham, Boshell Diabetes Building, Birmingham, AL 35233, USA.ORCID 0000-0002-0054-6957
Oluseun AkinyeleDepartment of Medicine, Division of General Internal Medicine and Population Science, University of Alabama at Birmingham, Boshell Diabetes Building, Birmingham, AL 35233, USA.
Abigail A NinsonEmbrace Society, 16 Otele Avenue, East Legon, Accra 233-030, Ghana.
Nicole Caviness-AsheDepartment of Medicine, Division of General Internal Medicine and Population Science, University of Alabama at Birmingham, Boshell Diabetes Building, Birmingham, AL 35233, USA.ORCID 0000-0002-6593-3827
Cha'Breia MeansDepartment of Medicine, Division of General Internal Medicine and Population Science, University of Alabama at Birmingham, Boshell Diabetes Building, Birmingham, AL 35233, USA.ORCID 0009-0007-2369-8754
Le'Andrea Anderson-TolbertDepartment of Medicine, Division of General Internal Medicine and Population Science, University of Alabama at Birmingham, Boshell Diabetes Building, Birmingham, AL 35233, USA.ORCID 0009-0003-6983-7183
Tuchondriana SmithDepartment of Engineering, Alabama State University, 915 S. Jackson Street, Montgomery, AL 36104, USA.
Reagan ColemanDepartment of Medicine, Division of General Internal Medicine and Population Science, University of Alabama at Birmingham, Boshell Diabetes Building, Birmingham, AL 35233, USA.ORCID 0009-0005-1949-7680
Laura Q RogersDepartment of Medicine, Division of General Internal Medicine and Population Science, University of Alabama at Birmingham, Boshell Diabetes Building, Birmingham, AL 35233, USA.ORCID 0000-0003-4216-8381
Joshua J JosephDivision of Endocrinology, Diabetes and Metabolism, The Ohio State University Wexner Medical Center Suite 5000 E, 700 Ackerman Road, Columbus, OH 43202, USA.
Laura C PinheiroDivision of General Internal Medicine, Department of Medicine, 420 East 70th Street, Room LH-359, Box 331, New York, NY 10021, USA.
Timiya S NolanDepartment of Medicine, Division of General Internal Medicine and Population Science, University of Alabama at Birmingham, Boshell Diabetes Building, Birmingham, AL 35233, USA.ORCID 0000-0002-6700-3105

Funding

MECHANISMS OF HYPERTENSION AND CARDIOVASCULAR DISEASEST32HL007457 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Martin E Young · 1985 to 2026
$8.6M
Piloting Y-AMBIENT: A Quality of Life Intervention for Young African American Breast Cancer Survivors in TreatmentK08CA245208 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI NOLAN, TIMIYA S · 2020 to 2024
$895k
National Heart, Lung & Blood Institute T32 HL0007457 (Miles)NCI NIH HHS K08 CA245208NCI NIH HHS K08CA245208 (Nolan)NHLBI NIH HHS T32 HL007457
6 · The paper itself

Abstract

Cardiovascular disease (CVD) is the most common non-cancer cause of death among cancer survivors. Lifestyle and clinical factors associated with cancer mortality are also associated with cardiovascular mortality. The American Heart Association (AHA) has termed these factors "cardiovascular health" (CVH), using Life's Simple 7 (LS7) or "Life's Essential 8 (LE8)" to determine poor, intermediate, and high (ideal) CVH. Further, less than ideal CVH is associated with higher cancer mortality. Yet, CVH among cancer survivors remains understudied. This systematic review examined the extant literature, providing a comprehensive report of the findings addressing CVH among cancer survivors.

methodsUsing PRISMA guidelines, we systematically examined CVH among cancer survivors (including patients) within PubMed, Scopus, CINAHL, and Embase databases without date limitations from June 2024 to December 2024 using the following keywords: "cancer survivors", "cancer patient", "cardiovascular health", and "cardiovascular risk factors". Two reviewers independently accessed articles in concordance with LS7 and LE8 metrics. The included studies were examined and assessed for risk of bias and synthesized to elucidate themes of CVH among cancer survivors.

resultsWe retrieved 2935 studies examining breast, gynecological, endometrial, prostate, colon, lung, lymphoma, and skin cancer survivors published from 2002-2024. Overall, 10 studies met criteria utilizing LS7 or LE8 CVH health outcomes (4 LS7, 5 LE8, and 1 LS7/LE8), ages 40-70 years, with a population (n = 35,980) consisting of mostly female, non-Black individuals; mean survivorship was 7.2 years. Four themes emerged: CVH outcomes among cancer survivors, social factors impacting CVH outcomes, associations of CVH, and other health outcomes opportunities for CVH awareness.

conclusionsWe found that cancer survivors frequently report less than ideal CVH outcomes and would benefit from education/empowerment to support lifestyle changes that improve CVH.

Indexed as

Cancer SurvivorsCardiovascular DiseasesNeoplasmsHumanscancer survivorshipcardiovascular healthpsychosocial health

Identifiers

PMID40566347
PMCPMC12193435

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.