Evidence map›Paper›PMID 40566953›Full record

ReviewBJPsych open2025

Epilepsy and psychosis: navigating through a complex intersection.

Marco Mula, Andres M Kanner, Allan H Young, Annabella Di Giorgio, Andreas Schulze-Bonhage, Eugen Trinka

Abstract readReview
In one paragraph

Review in BJPsych open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marco MulaDepartment of Neurology, St George's University Hospital, London, UK.ORCID https://orcid.org/0000-0002-9415-3395
Andres M KannerEpilepsy Division and Comprehensive Epilepsy Center, Department of Neurology, University of Miami, Miller School of Medicine, Miami, Florida, USA.
Allan H YoungDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID https://orcid.org/0000-0003-2291-6952
Annabella Di GiorgioDepartment of Mental Health and Addictions, ASST Papa Giovanni XXIII, Bergamo, Italy.
Andreas Schulze-BonhageEpilepsy Center, University Medical Center, University of Freiburg, Member of European Reference Network EpiCARE, Freiburg, Germany.
Eugen TrinkaDepartment of Neurology, Neurocritical Care and Neurorehabilitation, Member of European Reference Network EpiCARE, Centre for Cognitive Neuroscience, Christian Doppler University Hospital, Paracelsus Medical University, Salzburg, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of psychiatric disorders in people with epilepsy is as high as 43% and, among them, psychoses represent a severe comorbidity.

aimsThis is a narrative review discussing the interplay between epilepsy and psychosis and identifying challenges in diagnosing and managing psychotic symptoms in epilepsy, focusing on the past 10 years.

methodArticles published between June 2014 and December 2024 were identified through searches in PubMed using the search terms 'psychosis', 'seizure, epilepsy and convulsion', 'epile*', 'seizure*' and 'convuls*'.

resultsThe association between epilepsy and psychosis was shown to be bidirectional, with people with psychosis being at increased risk of epilepsy. In epilepsy, psychotic symptoms may occur in three clinical scenarios, with clinical presentation and management varying in relationship to these: seizure-related (peri-ictal), treatment-related or independent of the former.

conclusionsThere are no guidelines for the management of psychotic symptoms in epilepsy, but it is possible to apply policies for the treatment of psychoses, taking into account the peculiarities and needs of people with epilepsy.

Indexed as

antipsychotic drugsantiseizure drugsEpilepsylurasidonepsychosis

Identifiers

PMID40566953
PMCPMC12247078

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.