Evidence mapPaperPMID 40567164Full record

ArticleZoological research2025

Static magnetic field exposure modulates gut microbiota and host metabolism to alleviate high-fat diet-induced metabolic dysfunction-associated fatty liver disease.

Guo-Fu Chen, Juan-Juan Liu, Jing-Ming Fu, Chuan-Lin Feng, Guo-Feng Cheng, Ze-Min Fang, Xin Zhang, Xiao-Fei Tian

Abstract read
In one paragraph

Article in Zoological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guo-Fu ChenInstitute of Health Sciences and Technology, Institutes of Physical Sciences and Information Technology, Anhui University, Hefei, Anhui 230601, China.
Juan-Juan LiuSchool of life Sciences, Anhui University, Hefei, Anhui 230601, China.
Jing-Ming FuInstitute of Health Sciences and Technology, Institutes of Physical Sciences and Information Technology, Anhui University, Hefei, Anhui 230601, China.
Chuan-Lin FengScience Island Branch of Graduate School, University of Science and Technology of China, Hefei, Anhui 230031, China.
Guo-Feng ChengScience Island Branch of Graduate School, University of Science and Technology of China, Hefei, Anhui 230031, China.
Ze-Min FangSchool of life Sciences, Anhui University, Hefei, Anhui 230601, China.
Xin ZhangInstitute of Health Sciences and Technology, Institutes of Physical Sciences and Information Technology, Anhui University, Hefei, Anhui 230601, China.
Xiao-Fei TianInstitute of Health Sciences and Technology, Institutes of Physical Sciences and Information Technology, Anhui University, Hefei, Anhui 230601, China. E-mail: xiaofeitian@ahu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Static magnetic field (SMF) exposure exerts notable regulatory effects on metabolic disorders, yet its influence on metabolic dysfunction-associated fatty liver disease (MAFLD) and gut microbiota during disease progression remains unclear. In this study, MAFLD was induced in mice via a high-fat diet (HFD), followed by exposure to a 0.2 T SMF for 12 h per day over a 10 week period. SMF treatment significantly attenuated body weight gain, alleviated hepatic lipid accumulation, and improved liver function. Sequencing analysis of intestinal contents revealed a significant increase in microbial diversity and enrichment of beneficial bacterial taxa under SMF exposure. Integrated multi-omics analysis and Spearman correlation further demonstrated that SMF significantly reduced the expression of genes involved in fatty acid synthesis and modulated pathways related to polyunsaturated fatty acid and glutamate metabolism, in close association with shifts in beneficial gut microbiota. Furthermore, transcriptomic profiling of liver tissue indicated that SMF inhibited fatty acid synthesis and elongation by regulating the expression of peroxisome proliferator-activated receptor γ (

Indexed as

Diet, High-FatFatty LiverGastrointestinal MicrobiomeMagnetic FieldsAnimalsLiverMaleMetabolic DiseasesMiceMice, Inbred C57BLGut microbiotaMetabolic dysfunction-associated fatty liver diseaseMetabolitesMiceStatic magnetic fields

Identifiers

PMID40567164
PMCPMC12464374

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.