Evidence mapPaperPMID 40567404Full record

ArticleLaryngoscope investigative otolaryngology2025

Multilevel Associations of Food Environment and Papillary Thyroid Cancer Outcomes in the United States.

David J Fei-Zhang, Eric Pan, Jean-Nicolas Gallant, Andrés M Bur, Ryan H Belcher

Abstract read
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Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David J Fei-ZhangDepartment of Otolaryngology - Head and Neck Surgery Northwestern University Feinberg School of Medicine Chicago Illinois USA.ORCID https://orcid.org/0000-0002-4485-8274
Eric PanMedical College of Georgia - Augusta University Augusta Georgia USA.ORCID https://orcid.org/0009-0005-8575-9482
Jean-Nicolas GallantDepartment of Otorhinolaryngology - Head & Neck Surgery University of Pennsylvania Philadelphia Pennsylvania USA.
Andrés M BurDepartment of Otolaryngology-Head and Neck Surgery University of Kansas School of Medicine Kansas City Kansas USA.ORCID https://orcid.org/0000-0001-6879-6453
Ryan H BelcherDepartment of Otolaryngology-Head & Neck Surgery Vanderbilt University Medical Center Nashville Tennessee USA.ORCID https://orcid.org/0000-0002-9490-3694

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess the independent associations of poor food environment with differences in papillary thyroid carcinoma (PTC) outcomes using the United States Department of Agriculture (USDA)-validated Food Environment Atlas (FEA). Methods: This retrospective cohort study assessed patients from 2000 to 2017 for trends in overall and 3-year survival, and the number of tumors at diagnosis with increasing food environment vulnerability/FEA-scores by Cox hazards and logistic regression models stratified by race-ethnicity and age. FEA-scores were based on 282 county-level variables of food security, store-restaurant availability, SNAP/WIC enrollment, pricing, taxes, and producer vicinity while adjusting for traditional social determinant factors. Results: Among 148,296 patients, increased food environment vulnerability was associated with decreased overall survival (HR 1.06, 95% CI 1.04-1.07). These FEA effects were exacerbated among non-White patients (1.08, 1.05-1.11) compared to White patients (1.05, 1.04-1.07). Increased FEA was also associated with increased 3-year mortality (OR 1.05, 95% CI 1.03-1.07). These effects were exacerbated among non-White (1.06, 1.02-1.10) and older patients (1.05, 1.02-1.07). Increased food environment vulnerability was additionally associated with increased odds of having more than one primary tumor (1.02, 95% CI 1.01-1.03). When stratified separately for race and for age, worse food environment was associated with non-White patients (1.03, 1.01-1.06) and patients aged 45 years and older (1.02, 1.01-1.03). Conclusions: Food environment vulnerability was associated with poorer prognosis after adjusting for traditional social determinant vulnerabilities, with varying magnitude upon stratification of race and age. Given PTC's rise in incidence and severity, the effects of food environment should be considered when informing future investigation and policy. Level of Evidence: III.

Indexed as

food environmentnutritionpapillary thyroid cancerretrospective cohortsocial determinants of health

Identifiers

PMID40567404
PMCPMC12187614

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.