Evidence map›Paper›PMID 40568117›Full record

ArticlebioRxiv : the preprint server for biology2025

Immunization with peptide encapsulated within synthetic spores activates T cell responses and reduces tumor growth.

Domenico D'Atri, Elena Tondini, Federico Machinandiarena, Minsuk Kong, Alilin Mia, Devorah Gallardo, Kandice Tanner, Stephen M Hewitt, David J Fitzgerald, Kumaran S Ramamurthi

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Domenico D'AtriLaboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA.
Elena TondiniExperimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA.
Federico MachinandiarenaLaboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA.
Minsuk KongLaboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA.
Alilin MiaLaboratory Animal Sciences Program, Leidos Biomedical Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA.
Devorah GallardoLaboratory Animal Sciences Program, Leidos Biomedical Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA.
Kandice TannerLaboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA.
Stephen M HewittLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA.
David J FitzgeraldLaboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA.
Kumaran S RamamurthiLaboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptide-based therapeutic immunizations represent safe approaches to elicit antigen-specific T cell responses, but their broad utility remains limited due to poor immunogenicity and short

Identifiers

PMID40568117
PMCPMC12190748

What Socratic holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.