Evidence map›Paper›PMID 40568120›Full record

ArticlebioRxiv : the preprint server for biology2025

A single valine to leucine switch disrupts

Surendra K Prajapati, Jeffrey X Dong, Belinda J Morahan, Thoai Dotrang, Michelle C Barbeau, April E Williams, Daniel Hupalo, Matthew D Wilkerson, Clifton L Dalgard, Bjorn F C Kafsack and 2 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Surendra K PrajapatiDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, USA.ORCID 0000-0003-1188-668X
Jeffrey X DongDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, USA.ORCID 0009-0001-5558-2808
Belinda J MorahanLaboratory of Malaria and Vector Research, NIAID, NIH, Rockville, USA.
Thoai DotrangDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, USA.
Michelle C BarbeauDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, USA.
April E WilliamsDepartment of Molecular Biology, Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, USA.
Daniel HupaloDepartment of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences, Bethesda, USA.ORCID 0000-0001-7816-2948
Matthew D WilkersonDepartment of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences, Bethesda, USA.
Clifton L DalgardDepartment of Anatomy, Physiology & Genetics, Uniformed Services University of the Health Sciences, Bethesda, USA.ORCID 0000-0003-2025-8239
Bjorn F C KafsackDepartment of Microbiology & Immunology, Weill Cornell Medicine, New York, USA.ORCID 0000-0003-0089-1096
Manuel LlinásDepartment of Biochemistry & Molecular Biology and the Huck Center for Malaria Research, Pennsylvania State University, University Park, USA.ORCID 0000-0002-6173-5882
Kim C WilliamsonDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, USA.ORCID 0000-0003-2749-4082

Funding

Spatial Patterning During DevelopmentP50GM071508 · NIGMS · PRINCETON UNIVERSITY · PI POWELL, SUSAN M · 2004 to 2013
$30.6M
Plasmodium falciparum gametocytogenesisR01AI069314 · NIAID · LOYOLA UNIVERSITY OF CHICAGO · PI WILLIAMSON, KIM C · 2007 to 2017
$2.8M
Dissecting the role of ApiAP2 proteins in transcriptional regulation during Plasmodium falciparum developmentR01AI125565 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI LLINAS, MANUEL · 2016 to 2020
$1.9M
Regulation of Plasmodium falciparum transcriptionR01AI076276 · NIAID · PRINCETON UNIVERSITY · PI LLINAS, MANUEL · 2009 to 2013
$1.8M
Contribution of Pfs48/45 to Malaria Transmission-Blocking ImmunityR03AI103638 · NIAID · LOYOLA UNIVERSITY OF CHICAGO · PI WILLIAMSON, KIM C · 2013 to 2014
$134k
NIAID NIH HHS R01 AI069314NIAID NIH HHS R01 AI076276NIAID NIH HHS R01 AI125565NIAID NIH HHS R03 AI103638NIGMS NIH HHS P50 GM071508
6 · The paper itself

Abstract

Sexual commitment in

Identifiers

PMID40568120
PMCPMC12190761

What Socratic holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.