Evidence map›Paper›PMID 40568492›Full record

ArticleJournal of advanced veterinary and animal research2025

Fatty acids profile in Awassi sheep milk affected by some genes' single and combined effects.

Khaleel I Jawasreh, Dana Khrais, Muhammad Alu'datt, Nizar J Haddad, Sami Awabdeh, Mohammad Isam AlMadani, Mohamad Brake, Mohamad Ahmad Al-Araishi, Monther Sadder, Ahmad Al-Amareen

Abstract read
In one paragraph

Article in Journal of advanced veterinary and animal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Khaleel I JawasrehFaculty of Agriculture, Jordan University of Science and Technology (JUST), Irbid, Jordan.ORCID https://orcid.org/0000-0002-6576-4752
Dana KhraisFaculty of Agriculture, Jordan University of Science and Technology (JUST), Irbid, Jordan.ORCID https://orcid.org/0009-0002-7500-8798
Muhammad Alu'dattFaculty of Agriculture, Jordan University of Science and Technology (JUST), Irbid, Jordan.ORCID https://orcid.org/0000-0002-8976-5004
Nizar J HaddadNational Agriculture Research Center (NARC), Baqa`a, Jordan.ORCID https://orcid.org/0000-0003-0250-5291
Sami AwabdehNational Agriculture Research Center (NARC), Baqa`a, Jordan.ORCID https://orcid.org/0000-0001-7039-1172
Mohammad Isam AlMadaniQatar University, Qatar University Press, Qatar University, Doha, Qatar.ORCID https://orcid.org/0000-0002-5706-7922
Mohamad BrakeScience Faculty, Jerash University, Jerash, Jordan.ORCID https://orcid.org/0000-0003-3364-6273
Mohamad Ahmad Al-AraishiScience Faculty, Jerash University, Jerash, Jordan.ORCID https://orcid.org/0000-0002-6124-5584
Monther SadderFaculty of Agriculture, The University of Jordan, Amman, Jordan.ORCID https://orcid.org/0000-0001-6651-0423
Ahmad Al-AmareenNational Agriculture Research Center (NARC), Baqa`a, Jordan.ORCID https://orcid.org/0000-0002-2018-157X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study intended to figure out the effects of fixed effects and genes such as beta-lactoglobulin (β-LG), prolactin (PRL), annexin A9 (ANXA9), and acetyl-CoA acyltransferase 2 (ACAA2) on the structure of fatty milk acids in Awassi ewes, as well as any potential genotype-genotype interactions. Materials and Methods: Fatty acid (FA) profile and other milk components were examined from 116 Awassi ewes in total. Polymerase chain reaction (PCR) was used to extract and genotype their DNA, and either sequencing or restriction fragment length polymorphism (RFLP) analysis came next. Results: Saturated, medium-chain, and long-chain FA proportions were not significantly impacted by the genotypes of β-LG, PRL, ANXA9, and ACAA2. Conversely, ewes with the β-LG AA genotype displayed higher levels of monounsaturated fatty acids (MUFAs), while the β-LG AB genotype was linked to the highest levels of polyunsaturated fatty acids (PUFAs). It has been demonstrated that PUFA levels are impacted by single nucleotide polymorphisms (SNPs) of ANXA9, while VLCFA and PUFA levels are changed by SNPs of ACAA2. The PRL AA genotype showed the greatest influence on VLCFA. Furthermore, milk exhibited the highest levels of MUFA and PUFA due to the interaction between β-LG and PRL. The interaction PRL-ANXA9 exhibited the greatest levels of VLCFA. Additionally, Dam lambing weight affected the levels of MUFA, MCFA, and long-chain fatty acids. Conclusion: To increase the levels of MUFA and PUFA constituents, the selection program should effectively harness and integrate the synergistic benefits of β-LG, PRL, ANXA9, and ACAA2 as well as their interaction.

Indexed as

Awassi ewesfatty acidsgene interaction

Identifiers

PMID40568492
PMCPMC12186799

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.