Evidence map›Paper›PMID 40568809›Full record

ReviewNeurodegenerative disease management2025

Next-generation neurotherapeutics: nanotechnology, immunotherapy, and gene editing for neurodegenerative diseases.

Sameer Chaudhary, Sakshi Rawat, Sakshi Mathur, Asma Perveen, Abdul Hafeez, Anwar L Bilgrami, Ghulam Md Ashraf

Abstract readReview
In one paragraph

Review in Neurodegenerative disease management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sameer ChaudharyRASA Life science Informatics, Pune, India.
Sakshi RawatRASA Life science Informatics, Pune, India.
Sakshi MathurRASA Life science Informatics, Pune, India.
Asma PerveenDepartment of Biochemistry, Faculty of Life Sciences, Aligarh Muslim University, Aligarh, India.
Abdul HafeezGlocal University Pharmacy College, Glocal University, Saharanpur, India.
Anwar L BilgramiDeanship of Scientific Research, King Abdulaziz University, Jeddah, Saudi Arabia.
Ghulam Md AshrafDepartment of Biosciences and Bioinformatics, School of Science, Xi'an Jiaotong-Liverpool University, Suzhou, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurodegenerative disorders (NDDs), characterized by gradual decline of neuronal function and structure, present a major threat to global public health. Recent advances in neuropharmacology have opened promising avenues for novel therapeutic approaches. This review highlights promising neuropharmacological targets that may alleviate the debilitating effects of neurodegenerative disorders. This review examines established yet emerging molecular targets in neurodegeneration, including protein aggregation, synaptic dysfunction, oxidative stress, neuroinflammation, and Rho-associated protein kinase (ROCK) signaling. The review also explores ground-breaking therapeutic strategies that have transformed modern neuropharmacology. Recent advances in nanotechnology, gene therapy, immunotherapy, and

Indexed as

Gene EditingGenetic TherapyImmunotherapyNanotechnologyNeurodegenerative DiseasesAnimalsHumansDrug delivery systemneurodegenerationneuroprotectionpharmacological targetsRho-associated protein kinase

Identifiers

PMID40568809
PMCPMC12952745

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.